Possible methods for evaluation of hydrogen sulfide toxicity against lactic acid bacteria
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F19%3A00110411" target="_blank" >RIV/00216224:14310/19:00110411 - isvavai.cz</a>
Výsledek na webu
<a href="http://biointerfaceresearch.com/?page_id=4269" target="_blank" >http://biointerfaceresearch.com/?page_id=4269</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.33263/BRIAC94.066069" target="_blank" >10.33263/BRIAC94.066069</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Possible methods for evaluation of hydrogen sulfide toxicity against lactic acid bacteria
Popis výsledku v původním jazyce
An integral part of the intestinal microbiota is undoubtedly formed by lactic acid bacteria (LAB). Their presence in the digestive tract is essential for its proper functioning. During inflammatory bowel disease, such as ulcerative colitis (UC), LAB occurrence is reduced while sulfate-reducing bacteria (SRB) occur widely in the intestine resulting in an increase of their metabolite, hydrogen sulfide. Inhibitory concentration and mechanism of action of hydrogen sulfide on LAB are not fully known yet. The aim of this paper is to find the proper testing methods for evaluation of the interaction between hydrogen sulfide and lactic acid bacteria, including minimal inhibitory concentration (MIC) determination. Spectrophotometric, colorimetric, agar plate methods and combination of these methods were tested. Thousands of people from all over the world are affected by inflammatory bowel disease every year. The gained results could help to understand and improve the stability of intestinal microbiome, improve the treatment of bowel inflammation diseases, or prevent bowel disease altogether.
Název v anglickém jazyce
Possible methods for evaluation of hydrogen sulfide toxicity against lactic acid bacteria
Popis výsledku anglicky
An integral part of the intestinal microbiota is undoubtedly formed by lactic acid bacteria (LAB). Their presence in the digestive tract is essential for its proper functioning. During inflammatory bowel disease, such as ulcerative colitis (UC), LAB occurrence is reduced while sulfate-reducing bacteria (SRB) occur widely in the intestine resulting in an increase of their metabolite, hydrogen sulfide. Inhibitory concentration and mechanism of action of hydrogen sulfide on LAB are not fully known yet. The aim of this paper is to find the proper testing methods for evaluation of the interaction between hydrogen sulfide and lactic acid bacteria, including minimal inhibitory concentration (MIC) determination. Spectrophotometric, colorimetric, agar plate methods and combination of these methods were tested. Thousands of people from all over the world are affected by inflammatory bowel disease every year. The gained results could help to understand and improve the stability of intestinal microbiome, improve the treatment of bowel inflammation diseases, or prevent bowel disease altogether.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10606 - Microbiology
Návaznosti výsledku
Projekt
—
Návaznosti
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2019
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Biointerface Research in Applied Chemistry
ISSN
2069-5837
e-ISSN
—
Svazek periodika
9
Číslo periodika v rámci svazku
4
Stát vydavatele periodika
RO - Rumunsko
Počet stran výsledku
4
Strana od-do
4066-4069
Kód UT WoS článku
000486974400013
EID výsledku v databázi Scopus
2-s2.0-85073286394