Looking at the health of past populations through the lens of human dental calculus

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F19%3A00110957" target="_blank" >RIV/00216224:14310/19:00110957 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Looking at the health of past populations through the lens of human dental calculus

Popis výsledku v původním jazyce

Connection of ancient human dental calculus and molecular biology has so far brought up more questions than answers. Dental calculus is a calcified dental plaque and as such, it is mostly composed of bacteria and their products. This opens a door to the research of oral health as well as pathogens found in blood or respiratory system. The presented study shows the potential of molecular research of ancient human dental calculus in connection with health and the problems with authentication of acquired results. Several potential pathogens were detected by sequencing of 16S rDNA in Early Medieval specimens, but an even greater quantity of contaminating organisms was found. How does that change the usefulness of the applied approach? Is there a right way for the interpretation of metagenomic data derived from ancient samples?

Název v anglickém jazyce

Looking at the health of past populations through the lens of human dental calculus

Popis výsledku anglicky

Connection of ancient human dental calculus and molecular biology has so far brought up more questions than answers. Dental calculus is a calcified dental plaque and as such, it is mostly composed of bacteria and their products. This opens a door to the research of oral health as well as pathogens found in blood or respiratory system. The presented study shows the potential of molecular research of ancient human dental calculus in connection with health and the problems with authentication of acquired results. Several potential pathogens were detected by sequencing of 16S rDNA in Early Medieval specimens, but an even greater quantity of contaminating organisms was found. How does that change the usefulness of the applied approach? Is there a right way for the interpretation of metagenomic data derived from ancient samples?

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10608 - Biochemistry and molecular biology

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů