Hydrophilic Poly(2-Oxazoline) Coatings Prepared By Non-Equilibrium “Cold” Atmospheric Pressure Plasma

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F19%3A00112052" target="_blank" >RIV/00216224:14310/19:00112052 - isvavai.cz</a>

Výsledek na webu

<a href="https://munispace.muni.cz/library/catalog/book/1419" target="_blank" >https://munispace.muni.cz/library/catalog/book/1419</a>

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Hydrophilic Poly(2-Oxazoline) Coatings Prepared By Non-Equilibrium “Cold” Atmospheric Pressure Plasma

Popis výsledku v původním jazyce

Due to biological inertness and excellent stability, polytetrafluoroethylene (PTFE) is extensively used for the manufacturing of vascular grafts and various implants. However, its highly hydrophobic nature is disadvantageous for specific biomedical applications requiring the control of the proteins or cell adhesion. Hydrophobicity can be decreased by surface modification using the various biocompatible polymers. In our contribution, we proposed the new method for PTFE surface coating by synthetic hydrophilic polymers, so-called poly(2-oxazolines) (POx). Immobilization of the POx layer was performed employing non-equilibrium “cold” atmospheric pressure plasma generated by the diffuse coplanar surface barrier discharge (DCSBD). Our main objective was to achieve the stable and biologically active cross-linked POx layer immobilized on the PTFE surface. This study provides a new approach for the preparation of POx coatings, which is faster, easier, and more environmentally friendly in comparison to traditional grafting methods or plasma-assisted polymerization.

Název v anglickém jazyce

Hydrophilic Poly(2-Oxazoline) Coatings Prepared By Non-Equilibrium “Cold” Atmospheric Pressure Plasma

Popis výsledku anglicky

Due to biological inertness and excellent stability, polytetrafluoroethylene (PTFE) is extensively used for the manufacturing of vascular grafts and various implants. However, its highly hydrophobic nature is disadvantageous for specific biomedical applications requiring the control of the proteins or cell adhesion. Hydrophobicity can be decreased by surface modification using the various biocompatible polymers. In our contribution, we proposed the new method for PTFE surface coating by synthetic hydrophilic polymers, so-called poly(2-oxazolines) (POx). Immobilization of the POx layer was performed employing non-equilibrium “cold” atmospheric pressure plasma generated by the diffuse coplanar surface barrier discharge (DCSBD). Our main objective was to achieve the stable and biologically active cross-linked POx layer immobilized on the PTFE surface. This study provides a new approach for the preparation of POx coatings, which is faster, easier, and more environmentally friendly in comparison to traditional grafting methods or plasma-assisted polymerization.

Druh

O - Ostatní výsledky

CEP obor

—

OECD FORD obor

10305 - Fluids and plasma physics (including surface physics)

Projekt

<a href="/cs/project/EF16_027%2F0008360" target="_blank" >EF16_027/0008360: Postdoc@MUNI</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů