Molecular communication between the monogenea and fish immune system

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F21%3A00118845" target="_blank" >RIV/00216224:14310/21:00118845 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00027162:_____/21:N0000051

Výsledek na webu

<a href="https://doi.org/10.1016/j.fsi.2020.08.023" target="_blank" >https://doi.org/10.1016/j.fsi.2020.08.023</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.fsi.2020.08.023" target="_blank" >10.1016/j.fsi.2020.08.023</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Molecular communication between the monogenea and fish immune system

Popis výsledku v původním jazyce

Monogeneans parasitise mainly the outer structures of fish, such as the gills, fins, and skin, that is, tissues covered with a mucous layer. While attached by sclerotised structures to host's surface, monogeneans feed on its blood or epidermal cells and mucus. Besides being a rich source of nutrients, these tissues also contain humoral immune factors and immune cells, which are ready to launch defence mechanisms against the tegument or gastrointestinal tract of these invaders. The exploitation of hosts' resources by the Monogenea must, therefore, be accompanied by suppressive and immunomodulatory mechanisms which protect the parasites against attacks by host immune system. Elimination of hosts' cytotoxic molecules and evasion of host immune response is often mediated by proteins secreted by the parasites. The aim of this review is to summarise existing knowledge on fish immune responses against monogeneans. Results gleaned from experimental infections illustrate the various interactions between parasites and the innate and adaptive immune system of the fish. The involvement of monogenean molecules (mainly inhibitors of peptidases) in molecular communication with host immune system is discussed.

Název v anglickém jazyce

Molecular communication between the monogenea and fish immune system

Popis výsledku anglicky

Monogeneans parasitise mainly the outer structures of fish, such as the gills, fins, and skin, that is, tissues covered with a mucous layer. While attached by sclerotised structures to host's surface, monogeneans feed on its blood or epidermal cells and mucus. Besides being a rich source of nutrients, these tissues also contain humoral immune factors and immune cells, which are ready to launch defence mechanisms against the tegument or gastrointestinal tract of these invaders. The exploitation of hosts' resources by the Monogenea must, therefore, be accompanied by suppressive and immunomodulatory mechanisms which protect the parasites against attacks by host immune system. Elimination of hosts' cytotoxic molecules and evasion of host immune response is often mediated by proteins secreted by the parasites. The aim of this review is to summarise existing knowledge on fish immune responses against monogeneans. Results gleaned from experimental infections illustrate the various interactions between parasites and the innate and adaptive immune system of the fish. The involvement of monogenean molecules (mainly inhibitors of peptidases) in molecular communication with host immune system is discussed.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10613 - Zoology

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Fish and Shellfish Immunology

ISSN

1050-4648

e-ISSN

—

Svazek periodika

112

Číslo periodika v rámci svazku

May

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

12

Strana od-do

179-190

Kód UT WoS článku

000636145600004

EID výsledku v databázi Scopus

2-s2.0-85096463141