Geodesic fiber tracking in white matter using activation function

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F21%3A00119136" target="_blank" >RIV/00216224:14310/21:00119136 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68407700:21230/21:00354551

Výsledek na webu

<a href="https://doi.org/10.1016/j.cmpb.2021.106283" target="_blank" >https://doi.org/10.1016/j.cmpb.2021.106283</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.cmpb.2021.106283" target="_blank" >10.1016/j.cmpb.2021.106283</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Geodesic fiber tracking in white matter using activation function

Popis výsledku v původním jazyce

Background and objective:The geodesic ray-tracing method has shown its effectiveness for the reconstruction of fibers in white matter structure. Based on reasonable metrics on the spaces of the diffusion tensors, it can provide multiple solutions and get robust to noise and curvatures of fibers. The choice of the metric on the spaces of diffusion tensors has a significant impact on the outcome of this method. Our objective is to suggest metrics and modifications of the algorithms leading to more satisfactory results in the construction of white matter tracts as geodesics. Methods:Starting with the DTI modality, we propose to rescale the initially chosen metric on the space of diffusion tensors to increase the geodetic cost in the isotropic regions. This change should be conformal in order to preserve the angles between crossing fibers. We also suggest to enhance the methods to be more robust to noise and to employ the fourth order tensor data in order to handle the fiber crossings properly. Results: We propose a way to choose the appropriate conformal class of metrics where the metric gets scaled according to tensor anisotropy. We use the logistic functions, which are commonly used in statistics as cumulative distribution functions. To prevent deviation of geodesics from the actual paths, we propose a hybrid ray-tracing approach. Furthermore, we suggest how to employ diagonal projections of 4th order tensors to perform fiber tracking in crossing regions. Conclusions: The algorithms based on the newly suggested methods were succesfuly implemented, their performance was tested on both synthetic and real data, and compared to some of the previously known approaches.

Název v anglickém jazyce

Geodesic fiber tracking in white matter using activation function

Popis výsledku anglicky

Background and objective:The geodesic ray-tracing method has shown its effectiveness for the reconstruction of fibers in white matter structure. Based on reasonable metrics on the spaces of the diffusion tensors, it can provide multiple solutions and get robust to noise and curvatures of fibers. The choice of the metric on the spaces of diffusion tensors has a significant impact on the outcome of this method. Our objective is to suggest metrics and modifications of the algorithms leading to more satisfactory results in the construction of white matter tracts as geodesics. Methods:Starting with the DTI modality, we propose to rescale the initially chosen metric on the space of diffusion tensors to increase the geodetic cost in the isotropic regions. This change should be conformal in order to preserve the angles between crossing fibers. We also suggest to enhance the methods to be more robust to noise and to employ the fourth order tensor data in order to handle the fiber crossings properly. Results: We propose a way to choose the appropriate conformal class of metrics where the metric gets scaled according to tensor anisotropy. We use the logistic functions, which are commonly used in statistics as cumulative distribution functions. To prevent deviation of geodesics from the actual paths, we propose a hybrid ray-tracing approach. Furthermore, we suggest how to employ diagonal projections of 4th order tensors to perform fiber tracking in crossing regions. Conclusions: The algorithms based on the newly suggested methods were succesfuly implemented, their performance was tested on both synthetic and real data, and compared to some of the previously known approaches.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10102 - Applied mathematics

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Computer Methods and Programs in Biomedicine

ISSN

0169-2607

e-ISSN

—

Svazek periodika

208

Číslo periodika v rámci svazku

September

Stát vydavatele periodika

IE - Irsko

Počet stran výsledku

14

Strana od-do

„106283“

Kód UT WoS článku

000685504200002

EID výsledku v databázi Scopus

2-s2.0-85111293735