Oral microbiota in patients with oral squamous cell carcinoma

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F22%3A00126565" target="_blank" >RIV/00216224:14310/22:00126565 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Oral microbiota in patients with oral squamous cell carcinoma

Popis výsledku v původním jazyce

Oral squamous cell carcinoma (OSCC) is the most common malignancy in the head and neck region and, despite advances in treatment, is often diagnosed only at a late stage and has a poor prognosis. Oral carcinogenesis is a multifactorial process involving the effect of the exposome and subsequent cytogenetic and epigenetic changes in keratinocytes. External risk factors include tobacco, alcohol abuse, and malhygiene, which can affect the composition of the oral microbiota. 1 Oral microbiota (bacteriome, mycobiome, and virome) has been associated with oral cancer through a wide range of mechanisms2 , but the relationship has not been thoroughly characterized.

Název v anglickém jazyce

Oral microbiota in patients with oral squamous cell carcinoma

Popis výsledku anglicky

Oral squamous cell carcinoma (OSCC) is the most common malignancy in the head and neck region and, despite advances in treatment, is often diagnosed only at a late stage and has a poor prognosis. Oral carcinogenesis is a multifactorial process involving the effect of the exposome and subsequent cytogenetic and epigenetic changes in keratinocytes. External risk factors include tobacco, alcohol abuse, and malhygiene, which can affect the composition of the oral microbiota. 1 Oral microbiota (bacteriome, mycobiome, and virome) has been associated with oral cancer through a wide range of mechanisms2 , but the relationship has not been thoroughly characterized.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10608 - Biochemistry and molecular biology

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů