Human exposure to polycyclic aromatic hydrocarbons in the atmosphere of an agricultural area of central Chile and inhalation cancer risk assessments

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F23%3A00131218" target="_blank" >RIV/00216224:14310/23:00131218 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S1309104223000491?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1309104223000491?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.apr.2023.101695" target="_blank" >10.1016/j.apr.2023.101695</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Human exposure to polycyclic aromatic hydrocarbons in the atmosphere of an agricultural area of central Chile and inhalation cancer risk assessments

Popis výsledku v původním jazyce

Polycyclic aromatic hydrocarbons (PAHs) are persistent toxic substances prone to long-range atmospheric transport. Even in low concentrations, environmental exposure to PAHs can impact human health. In this study we aimed to i) investigate the occurrence of 15 polycyclic aromatic hydrocarbons (Sigma 15PAHs), from August 2016 to January 2018, in the atmosphere of Molina, using polyurethane foam disks (PAS-PUF) in central Chile; and ii) perform deterministic and probabilistic (using Monte Carlo simulations) inhalation cancer risk assessments. Gas chromatography and tandem quadrupole mass spectrometry (GC-MS/MS) measured target PAHs. Results showed Sigma 15PAHs ranging from 2 ng m-3 to 108 ng m-3, with four-ring PAHs as the prevalent compounds, including phenanthrene (44%) and fluoranthene (24%). Winter season showed the highest PAH levels (increasing factor up to similar to 8 times). PAHs diagnostic ratios showed the prevalence of pyrogenic combustion (winter) and petrogenic combustion (summer). Lifetime cancer risk assessments, using BaP-eq values, indicated an increased cancer risk for the exposed population considering different risk assessment approaches. Younger individuals were the most affected by an increased cancer risk at all sampling sites. The Monte Carlo probabilistic assessment indicated that infants and toddlers could be exposed to PAH air concentrations exceeding the cancer risk threshold in over 94% of the simulations. The coldest months in the studied region are critical for human exposure and health risk due to intense wood combustion. Indoor air can be even more relevant due to the chronic inhalation of the smoke and associated chemicals.

Název v anglickém jazyce

Human exposure to polycyclic aromatic hydrocarbons in the atmosphere of an agricultural area of central Chile and inhalation cancer risk assessments

Popis výsledku anglicky

Polycyclic aromatic hydrocarbons (PAHs) are persistent toxic substances prone to long-range atmospheric transport. Even in low concentrations, environmental exposure to PAHs can impact human health. In this study we aimed to i) investigate the occurrence of 15 polycyclic aromatic hydrocarbons (Sigma 15PAHs), from August 2016 to January 2018, in the atmosphere of Molina, using polyurethane foam disks (PAS-PUF) in central Chile; and ii) perform deterministic and probabilistic (using Monte Carlo simulations) inhalation cancer risk assessments. Gas chromatography and tandem quadrupole mass spectrometry (GC-MS/MS) measured target PAHs. Results showed Sigma 15PAHs ranging from 2 ng m-3 to 108 ng m-3, with four-ring PAHs as the prevalent compounds, including phenanthrene (44%) and fluoranthene (24%). Winter season showed the highest PAH levels (increasing factor up to similar to 8 times). PAHs diagnostic ratios showed the prevalence of pyrogenic combustion (winter) and petrogenic combustion (summer). Lifetime cancer risk assessments, using BaP-eq values, indicated an increased cancer risk for the exposed population considering different risk assessment approaches. Younger individuals were the most affected by an increased cancer risk at all sampling sites. The Monte Carlo probabilistic assessment indicated that infants and toddlers could be exposed to PAH air concentrations exceeding the cancer risk threshold in over 94% of the simulations. The coldest months in the studied region are critical for human exposure and health risk due to intense wood combustion. Indoor air can be even more relevant due to the chronic inhalation of the smoke and associated chemicals.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10511 - Environmental sciences (social aspects to be 5.7)

Projekt

<a href="/cs/project/EF17_043%2F0009632" target="_blank" >EF17_043/0009632: CETOCOEN Excellence</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Atmospheric Pollution Research

ISSN

1309-1042

e-ISSN

—

Svazek periodika

14

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

TR - Turecká republika

Počet stran výsledku

9

Strana od-do

1-9

Kód UT WoS článku

000954833500001

EID výsledku v databázi Scopus

2-s2.0-85149231464