From Endothelial Progenitor Cells to Tissue Engineering: How Far Have We Come?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14330%2F14%3A00073592" target="_blank" >RIV/00216224:14330/14:00073592 - isvavai.cz</a>

Výsledek na webu

<a href="http://omicsonline.org/open-access/from-endothelial-progenitor-cells-tissue-engineering-2157-7633.1000185.php?aid=24407" target="_blank" >http://omicsonline.org/open-access/from-endothelial-progenitor-cells-tissue-engineering-2157-7633.1000185.php?aid=24407</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4172/2157-7633.1000185" target="_blank" >10.4172/2157-7633.1000185</a>

Jazyk výsledku

angličtina

Název v původním jazyce

From Endothelial Progenitor Cells to Tissue Engineering: How Far Have We Come?

Popis výsledku v původním jazyce

Cardiovascular disease has become the leading cause of death in high income countries worldwide and the available treatment is not able to provide a complete recovery. Tissue engineering offers a possibility to construct autologous vein replacements forsurgery. In this review we summarize approaches leading to artificial vascular graft construction. We discuss biomaterials currently in use, various drug delivery systems and the most appropriate cell cultures for vein engineering. Despite the progress in biomaterials and drug delivery systems, generating a suitable tissue microenvironment and selection of the appropriate cell population for graft seeding remains a major challenge. Here we focus on endothelial progenitor stem cells as the most suitablecell type for vascular graft construction. We discuss its sources, isolation techniques and differentiation procedures.

Název v anglickém jazyce

From Endothelial Progenitor Cells to Tissue Engineering: How Far Have We Come?

Popis výsledku anglicky

Cardiovascular disease has become the leading cause of death in high income countries worldwide and the available treatment is not able to provide a complete recovery. Tissue engineering offers a possibility to construct autologous vein replacements forsurgery. In this review we summarize approaches leading to artificial vascular graft construction. We discuss biomaterials currently in use, various drug delivery systems and the most appropriate cell cultures for vein engineering. Despite the progress in biomaterials and drug delivery systems, generating a suitable tissue microenvironment and selection of the appropriate cell population for graft seeding remains a major challenge. Here we focus on endothelial progenitor stem cells as the most suitablecell type for vascular graft construction. We discuss its sources, isolation techniques and differentiation procedures.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

<a href="/cs/project/GBP302%2F12%2FG157" target="_blank" >GBP302/12/G157: Dynamika a organizace chromosomů během buněčného cyklu a při diferenciaci v normě a patologii</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Stem Cell Research & Therapy

ISSN

2157-7633

e-ISSN

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Svazek periodika

4

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

11

Strana od-do

185

Kód UT WoS článku

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EID výsledku v databázi Scopus

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