Methylation of plant telomeric DNA: what do the results say?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F11%3A00049500" target="_blank" >RIV/00216224:14740/11:00049500 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s11103-011-9834-5" target="_blank" >http://dx.doi.org/10.1007/s11103-011-9834-5</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11103-011-9834-5" target="_blank" >10.1007/s11103-011-9834-5</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Methylation of plant telomeric DNA: what do the results say?

Popis výsledku v původním jazyce

Recently, we reported (Majerova et al. 2011) that hypomethylating drugs efficiently decrease methylation of telomeric DNA and activate telomerase without affecting telomere lengths in tobacco. The key issue of the Letter to Editor written by Vaquero-Sedas and Vega-Palas (2011) is, whether our results demonstrating methylation and druginduced hypomethylation of tobacco telomeric DNA repeats do correspond to the status of terminal telomeric sequences, or rather to internal telomeric sequences (ITSs) whichmight exist in tobacco genome as it is the case in Arabidopsis thaliana, the model organism which Vaquero- Sedas and Vega-Palas have been working with. They are referring to their recent article (Vaquero-Sedas et al. 2010) in which they conclude that ITSs in A. thaliana are heterochromatic, while telomeres are euchromatic. We are pleased that our paper has initiated this debate and take the opportunity to go through the key points of the Letter of Vaquero-Sedas and Vega-Palas

Název v anglickém jazyce

Methylation of plant telomeric DNA: what do the results say?

Popis výsledku anglicky

Recently, we reported (Majerova et al. 2011) that hypomethylating drugs efficiently decrease methylation of telomeric DNA and activate telomerase without affecting telomere lengths in tobacco. The key issue of the Letter to Editor written by Vaquero-Sedas and Vega-Palas (2011) is, whether our results demonstrating methylation and druginduced hypomethylation of tobacco telomeric DNA repeats do correspond to the status of terminal telomeric sequences, or rather to internal telomeric sequences (ITSs) whichmight exist in tobacco genome as it is the case in Arabidopsis thaliana, the model organism which Vaquero- Sedas and Vega-Palas have been working with. They are referring to their recent article (Vaquero-Sedas et al. 2010) in which they conclude that ITSs in A. thaliana are heterochromatic, while telomeres are euchromatic. We are pleased that our paper has initiated this debate and take the opportunity to go through the key points of the Letter of Vaquero-Sedas and Vega-Palas

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Plant Molecular Biology

ISSN

0167-4412

e-ISSN

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Svazek periodika

77

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

4

Strana od-do

533-536

Kód UT WoS článku

000299051300002

EID výsledku v databázi Scopus

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