DBS amplitude setting can improve aspects of quality of life in patients with Parkinson's disease

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F13%3A00070577" target="_blank" >RIV/00216224:14740/13:00070577 - isvavai.cz</a>

Výsledek na webu

<a href="http://europepmc.org/abstract/MED/23474852" target="_blank" >http://europepmc.org/abstract/MED/23474852</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00702-013-0990-4" target="_blank" >10.1007/s00702-013-0990-4</a>

Jazyk výsledku

angličtina

Název v původním jazyce

DBS amplitude setting can improve aspects of quality of life in patients with Parkinson's disease

Popis výsledku v původním jazyce

The DBS STN is a non-curative treatment; its effect on the patient's quality of life (QoL) determines the therapeutic success of this procedure. We aimed to assess whether stimulation parameters setting may influence also some of the non-motor aspects ofQoL. The QoL was assessed by PDQ-39 questionnaire. The questionnaire was administered to patients before and after the DBS surgery. A sham change of stimulation amplitude was performed before the actual increase. After the further amplitude increase insubgroup of patients (mean increase of amplitude of 0.35 V), there was a statistically significant additional improvement of total PDQ-39 score by another 22.9 %. In this group the emotions, stigma and communication subscales improved after the stimulation increase, without further change of UPDRS III.

Název v anglickém jazyce

DBS amplitude setting can improve aspects of quality of life in patients with Parkinson's disease

Popis výsledku anglicky

The DBS STN is a non-curative treatment; its effect on the patient's quality of life (QoL) determines the therapeutic success of this procedure. We aimed to assess whether stimulation parameters setting may influence also some of the non-motor aspects ofQoL. The QoL was assessed by PDQ-39 questionnaire. The questionnaire was administered to patients before and after the DBS surgery. A sham change of stimulation amplitude was performed before the actual increase. After the further amplitude increase insubgroup of patients (mean increase of amplitude of 0.35 V), there was a statistically significant additional improvement of total PDQ-39 score by another 22.9 %. In this group the emotions, stigma and communication subscales improved after the stimulation increase, without further change of UPDRS III.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

<a href="/cs/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: CEITEC - central european institute of technology</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Neural Transmission

ISSN

0300-9564

e-ISSN

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Svazek periodika

120

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

AT - Rakouská republika

Počet stran výsledku

6

Strana od-do

643-648

Kód UT WoS článku

000317076600022

EID výsledku v databázi Scopus

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