Disruption of Resting Functional Connectivity in Alzheimer's Patients and At-Risk Subjects

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F14%3A00074325" target="_blank" >RIV/00216224:14740/14:00074325 - isvavai.cz</a>

Výsledek na webu

<a href="http://link.springer.com/article/10.1007%2Fs11910-014-0491-3" target="_blank" >http://link.springer.com/article/10.1007%2Fs11910-014-0491-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11910-014-0491-3" target="_blank" >10.1007/s11910-014-0491-3</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Disruption of Resting Functional Connectivity in Alzheimer's Patients and At-Risk Subjects

Popis výsledku v původním jazyce

The resting brain exhibits continuous intrinsic activity, which is correlated between groups of regions forming resting state networks. Evaluating resting connectivity is a popular approach for studying brain diseases. Several hundred studies are now available that address integrity of resting connectivity in patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI), as well as preclinical at-risk subjects. Most studies focus on the default mode network, a system of specific brain areasshowing strong connected resting activity that attenuates during goal-directed behavior. The extent of intrinsic brain activity tends to be strongly correlated with cognitive processes and is specifically disrupted in AD and MCI patients and at-risk subjects, with changes seeming to evolve during the transition between the disease stages.

Název v anglickém jazyce

Disruption of Resting Functional Connectivity in Alzheimer's Patients and At-Risk Subjects

Popis výsledku anglicky

The resting brain exhibits continuous intrinsic activity, which is correlated between groups of regions forming resting state networks. Evaluating resting connectivity is a popular approach for studying brain diseases. Several hundred studies are now available that address integrity of resting connectivity in patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI), as well as preclinical at-risk subjects. Most studies focus on the default mode network, a system of specific brain areasshowing strong connected resting activity that attenuates during goal-directed behavior. The extent of intrinsic brain activity tends to be strongly correlated with cognitive processes and is specifically disrupted in AD and MCI patients and at-risk subjects, with changes seeming to evolve during the transition between the disease stages.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS

ISSN

1528-4042

e-ISSN

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Svazek periodika

14

Číslo periodika v rámci svazku

10

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

"nestránkované"

Kód UT WoS článku

000342073900008

EID výsledku v databázi Scopus

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