Cell Surface ABP1-TMK Auxin-Sensing Complex Activates ROP GTPase Signaling

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F14%3A00079364" target="_blank" >RIV/00216224:14740/14:00079364 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.sciencemag.org/content/343/6174/1025.full.pdf" target="_blank" >http://www.sciencemag.org/content/343/6174/1025.full.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1126/science.1245125" target="_blank" >10.1126/science.1245125</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Cell Surface ABP1-TMK Auxin-Sensing Complex Activates ROP GTPase Signaling

Popis výsledku v původním jazyce

Auxin-binding protein 1 (ABP1) was discovered nearly 40 years ago and was shown to be essential for plant development and morphogenesis, but its mode of action remains unclear. Here, we report that the plasma membrane-localized transmembrane kinase (TMK)receptor-like kinases interact with ABP1 and transduce auxin signal to activate plasma membrane-associated ROPs [Rho-like guanosine triphosphatases (GTPase) from plants], leading to changes in the cytoskeleton and the shape of leaf pavement cells in Arabidopsis. The interaction between ABP1 and TMK at the cell surface is induced by auxin and requires ABP1 sensing of auxin. These findings show that TMK proteins and ABP1 form a cell surface auxin perception complex that activates ROP signaling pathways,regulating nontranscriptional cytoplasmic responses and associated fundamental processes.

Název v anglickém jazyce

Cell Surface ABP1-TMK Auxin-Sensing Complex Activates ROP GTPase Signaling

Popis výsledku anglicky

Auxin-binding protein 1 (ABP1) was discovered nearly 40 years ago and was shown to be essential for plant development and morphogenesis, but its mode of action remains unclear. Here, we report that the plasma membrane-localized transmembrane kinase (TMK)receptor-like kinases interact with ABP1 and transduce auxin signal to activate plasma membrane-associated ROPs [Rho-like guanosine triphosphatases (GTPase) from plants], leading to changes in the cytoskeleton and the shape of leaf pavement cells in Arabidopsis. The interaction between ABP1 and TMK at the cell surface is induced by auxin and requires ABP1 sensing of auxin. These findings show that TMK proteins and ABP1 form a cell surface auxin perception complex that activates ROP signaling pathways,regulating nontranscriptional cytoplasmic responses and associated fundamental processes.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

<a href="/cs/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: CEITEC - central european institute of technology</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Science

ISSN

0036-8075

e-ISSN

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Svazek periodika

343

Číslo periodika v rámci svazku

6174

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

4

Strana od-do

1025-1028

Kód UT WoS článku

000332309600046

EID výsledku v databázi Scopus

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