Capillary electrophoresis in an extended nanospray tip-electrospray as an electrophoretic column

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F15%3A00081145" target="_blank" >RIV/00216224:14740/15:00081145 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68081715:_____/15:00447018

Výsledek na webu

<a href="http://ac.els-cdn.com/S002196731500299X/1-s2.0-S002196731500299X-main.pdf?_tid=fae1bcb8-7993-11e5-8ff8-00000aacb35f&acdnat=1445611398_373669954fc31a684ed5eccda5a4a52b" target="_blank" >http://ac.els-cdn.com/S002196731500299X/1-s2.0-S002196731500299X-main.pdf?_tid=fae1bcb8-7993-11e5-8ff8-00000aacb35f&acdnat=1445611398_373669954fc31a684ed5eccda5a4a52b</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.chroma.2015.02.042" target="_blank" >10.1016/j.chroma.2015.02.042</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Capillary electrophoresis in an extended nanospray tip-electrospray as an electrophoretic column

Popis výsledku v původním jazyce

Capillary electrophoresis coupled to mass spectrometry (CE/MS) is gaining its space among the most powerful tools in modern (bio)analytical laboratory. The most challenging instrumental aspect in CE/MS is striking the balance between the stability and reproducibility of the signal and sensitivity of the analysis. Several interface designs have been published in the past decade addressing the variety of instrumental aspects and ease of operation. Most of the interfaces can be categorized either into thesheath flow arrangement (considered to be a de facto standard), or sheathless interface, often expected to provide the ultimate sensitivity. In this work we have explored an "interface-free" approach, where the CE/MS analysis was performed in narrow bore(&lt;20 mu m ID) electrospray capillary. The separation capillary and electrospray tip formed one entity and the high voltage, applied at the injection end of the capillary served for both the separation and electrospray ionization.

Název v anglickém jazyce

Capillary electrophoresis in an extended nanospray tip-electrospray as an electrophoretic column

Popis výsledku anglicky

Capillary electrophoresis coupled to mass spectrometry (CE/MS) is gaining its space among the most powerful tools in modern (bio)analytical laboratory. The most challenging instrumental aspect in CE/MS is striking the balance between the stability and reproducibility of the signal and sensitivity of the analysis. Several interface designs have been published in the past decade addressing the variety of instrumental aspects and ease of operation. Most of the interfaces can be categorized either into thesheath flow arrangement (considered to be a de facto standard), or sheathless interface, often expected to provide the ultimate sensitivity. In this work we have explored an "interface-free" approach, where the CE/MS analysis was performed in narrow bore(&lt;20 mu m ID) electrospray capillary. The separation capillary and electrospray tip formed one entity and the high voltage, applied at the injection end of the capillary served for both the separation and electrospray ionization.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CE - Biochemie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Chromatography A

ISSN

0021-9673

e-ISSN

—

Svazek periodika

1388

Číslo periodika v rámci svazku

April

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

6

Strana od-do

274-279

Kód UT WoS článku

000351792400032

EID výsledku v databázi Scopus

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