The modulatory role of subthalamic nucleus in cognitive functions - A viewpoint.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F15%3A00082209" target="_blank" >RIV/00216224:14740/15:00082209 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S1388245714007263#" target="_blank" >http://www.sciencedirect.com/science/article/pii/S1388245714007263#</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.clinph.2014.10.156" target="_blank" >10.1016/j.clinph.2014.10.156</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The modulatory role of subthalamic nucleus in cognitive functions - A viewpoint.

Popis výsledku v původním jazyce

The modifications of electrophysiological activities of subthalamic nucleus (STN) by non-motor tasks, i.e. movement observation, emotional stimuli and impulse control, were reported repeatedly. Despite being a small structure, STN is apparently involvedin a variety of functions. Based on our own electrophysiological recordings and results of other groups we believe that it acts as an indirect modulator which may be involved in tuning the functional systems. STN may modulate specific cognitive activities via contextual modulation of certain cortical areas. Our findings support the hypothesis of a cortical-STN bypass (via hyperdirect pathway) of "classical" basal ganglia-thalamocortical circuitry, at least during the processing of certain cognitive functions. The modulation of cognitive functions appears to be selective, probably determined by the involvement of cortical neuronal populations interconnected with STN.

Název v anglickém jazyce

The modulatory role of subthalamic nucleus in cognitive functions - A viewpoint.

Popis výsledku anglicky

The modifications of electrophysiological activities of subthalamic nucleus (STN) by non-motor tasks, i.e. movement observation, emotional stimuli and impulse control, were reported repeatedly. Despite being a small structure, STN is apparently involvedin a variety of functions. Based on our own electrophysiological recordings and results of other groups we believe that it acts as an indirect modulator which may be involved in tuning the functional systems. STN may modulate specific cognitive activities via contextual modulation of certain cortical areas. Our findings support the hypothesis of a cortical-STN bypass (via hyperdirect pathway) of "classical" basal ganglia-thalamocortical circuitry, at least during the processing of certain cognitive functions. The modulation of cognitive functions appears to be selective, probably determined by the involvement of cortical neuronal populations interconnected with STN.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

<a href="/cs/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: CEITEC - central european institute of technology</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Clinical Neurophysiology

ISSN

1388-2457

e-ISSN

—

Svazek periodika

126

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

IE - Irsko

Počet stran výsledku

6

Strana od-do

653-658

Kód UT WoS článku

000351092100004

EID výsledku v databázi Scopus

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