Methodical approaches to PCR based quantification of miRNA in epilepsy
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F16%3A00088297" target="_blank" >RIV/00216224:14740/16:00088297 - isvavai.cz</a>
Výsledek na webu
<a href="http://www.epilepsyprague2016.org/" target="_blank" >http://www.epilepsyprague2016.org/</a>
DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Methodical approaches to PCR based quantification of miRNA in epilepsy
Popis výsledku v původním jazyce
microRNA(miRNA/miR) is a short noncoding RNA regulating gene expression on posttranscriptional level. The proper regulation by miRNA is essential for broad range of processes in the organism. Hence, the altered expression of miRNAs might be involved in various pathologies. Since 2010 is miRNA one of the important topics studied in the field of epilepsy. Altered miRNA profile seems to be contributing to the development of epilepsy and the disease progression. The accurate identification of miRNA profile of epilepsy and its subtypes would considerably contribute to the diagnostics and treatment of the disease. This presentation was focused on the methodical approaches used in the research of miRNA in epilepsy so far and the improvements in contemporary technologies of miRNA profiling. Recent advance in small RNA library preparation for Illumina sequencing reduces the bias in miRNA profile identification.
Název v anglickém jazyce
Methodical approaches to PCR based quantification of miRNA in epilepsy
Popis výsledku anglicky
microRNA(miRNA/miR) is a short noncoding RNA regulating gene expression on posttranscriptional level. The proper regulation by miRNA is essential for broad range of processes in the organism. Hence, the altered expression of miRNAs might be involved in various pathologies. Since 2010 is miRNA one of the important topics studied in the field of epilepsy. Altered miRNA profile seems to be contributing to the development of epilepsy and the disease progression. The accurate identification of miRNA profile of epilepsy and its subtypes would considerably contribute to the diagnostics and treatment of the disease. This presentation was focused on the methodical approaches used in the research of miRNA in epilepsy so far and the improvements in contemporary technologies of miRNA profiling. Recent advance in small RNA library preparation for Illumina sequencing reduces the bias in miRNA profile identification.
Klasifikace
Druh
O - Ostatní výsledky
CEP obor
FH - Neurologie, neurochirurgie, neurovědy
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/GA16-04726S" target="_blank" >GA16-04726S: miRNA a biochemické dráhy v epilepsii</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2016
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů