Web-based bioinformatic tool LYNX: LYmphoid NeXt-generation sequencing data analysis and visualization in hematological malignancies.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F23%3A00132767" target="_blank" >RIV/00216224:14740/23:00132767 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.embl.org/about/info/course-and-conference-office/events/can23-01/#vf-tabs__section-programme" target="_blank" >https://www.embl.org/about/info/course-and-conference-office/events/can23-01/#vf-tabs__section-programme</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Web-based bioinformatic tool LYNX: LYmphoid NeXt-generation sequencing data analysis and visualization in hematological malignancies.

Popis výsledku v původním jazyce

Next-generation sequencing (NGS) is rapidly advancing technology in cancer genomics. The single NGS experiment can replace several laboratory tests and provide requested information about the tumor samples. However, new requirements for bioinformatic tools and computational resources are emerging in diagnostics and research. Following the development of an integrative, targeted NGS panel LYNX, enabling the detection of genetic markers recurring in lymphoid malignancies (PMID: 34082072), we focused on designing a LYNX bioinformatics tool, featuring all necessary analytical steps as well as a user interface (UI) for easy data representation and interpretation. State-of-the art resources were used to achieve our goal, such as React.js, D3.js visualisation library, Integrated Genome Browser and GATK industry standard variant calling pipeline.

Název v anglickém jazyce

Web-based bioinformatic tool LYNX: LYmphoid NeXt-generation sequencing data analysis and visualization in hematological malignancies.

Popis výsledku anglicky

Next-generation sequencing (NGS) is rapidly advancing technology in cancer genomics. The single NGS experiment can replace several laboratory tests and provide requested information about the tumor samples. However, new requirements for bioinformatic tools and computational resources are emerging in diagnostics and research. Following the development of an integrative, targeted NGS panel LYNX, enabling the detection of genetic markers recurring in lymphoid malignancies (PMID: 34082072), we focused on designing a LYNX bioinformatics tool, featuring all necessary analytical steps as well as a user interface (UI) for easy data representation and interpretation. State-of-the art resources were used to achieve our goal, such as React.js, D3.js visualisation library, Integrated Genome Browser and GATK industry standard variant calling pipeline.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů