Palaeoproteomics of Dental Calculus: Exploring the Biomolecular Archive

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F25%3A00142334" target="_blank" >RIV/00216224:14740/25:00142334 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.ceitec.eu/2025-ceitec-iocb-symposium-for-early-career-researchers/a5312" target="_blank" >https://www.ceitec.eu/2025-ceitec-iocb-symposium-for-early-career-researchers/a5312</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Palaeoproteomics of Dental Calculus: Exploring the Biomolecular Archive

Popis výsledku v původním jazyce

Dental calculus, a calcified form of dental plaque, entraps and preserves a wide range of particles that enter the oral cavity during life. As a rich source of information, dental calculus has become a focal point in biomolecular archaeology, greatly expanding our understanding of past populations. Biomolecular research has revealed insights into the ancient oral microbiome, respiratory and oral pathogens, diet, habitual practices, identity and migration, as well as medicinal use of plants. In our project, we applied palaeoproteomic approaches to characterize the complex protein composition of ancient dental calculus. Samples originated from individuals buried at sites representing diverse geographical and temporal contexts. The most relevant and unique findings included plant-derived proteins with potential dietary or medicinal significance, together with numerous bacterial taxa, including putative pathogens. These results emphasize the potential of palaeoproteomics to unlock biomolecular information from dental calculus, demonstrating its value as a unique archive for reconstructing health, diet, and cultural practices in past populations.

Název v anglickém jazyce

Palaeoproteomics of Dental Calculus: Exploring the Biomolecular Archive

Popis výsledku anglicky

Dental calculus, a calcified form of dental plaque, entraps and preserves a wide range of particles that enter the oral cavity during life. As a rich source of information, dental calculus has become a focal point in biomolecular archaeology, greatly expanding our understanding of past populations. Biomolecular research has revealed insights into the ancient oral microbiome, respiratory and oral pathogens, diet, habitual practices, identity and migration, as well as medicinal use of plants. In our project, we applied palaeoproteomic approaches to characterize the complex protein composition of ancient dental calculus. Samples originated from individuals buried at sites representing diverse geographical and temporal contexts. The most relevant and unique findings included plant-derived proteins with potential dietary or medicinal significance, together with numerous bacterial taxa, including putative pathogens. These results emphasize the potential of palaeoproteomics to unlock biomolecular information from dental calculus, demonstrating its value as a unique archive for reconstructing health, diet, and cultural practices in past populations.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10608 - Biochemistry and molecular biology

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů