The leaves fall, yet the tree endures

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F25%3A00142435" target="_blank" >RIV/00216224:14740/25:00142435 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/article/10.1007/s00018-025-05874-8" target="_blank" >https://link.springer.com/article/10.1007/s00018-025-05874-8</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00018-025-05874-8" target="_blank" >10.1007/s00018-025-05874-8</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The leaves fall, yet the tree endures

Popis výsledku v původním jazyce

Aging in plants presents a paradox: while individual modules such as leaves and reproductive organs undergo senescence, the plant as a whole may display extraordinary longevity, enabled by its modular architecture and perpetually active meristems. This review explores aging and senescence in plants by challenging commonly held assumptions and integrating emerging insights from telomere biology and epigenetic regulation. We critically examine the role of telomere length as a determinant of replicative lifespan, arguing that its importance is often overstated, particularly in the context of plant systems where telomerase activity persists in meristematic tissues. In contrast, the epigenetic landscape-including DNA methylation, histone modifications, chromatin remodeling, and non-coding RNAs-plays a dynamic and increasingly appreciated role in orchestrating senescence at cellular and organ levels. We synthesize current understanding of how these chromatin-level mechanisms interact with developmental cues and environmental stresses to regulate genome stability, transcriptional reprogramming, and longevity. By integrating chromosomal and epigenetic processes, this review provides a refined conceptual framework for understanding plant aging and highlights new opportunities to enhance resilience and lifespan in crops and long-lived species through targeted manipulation of telomere maintenance and epigenetic pathways.

Název v anglickém jazyce

The leaves fall, yet the tree endures

Popis výsledku anglicky

Aging in plants presents a paradox: while individual modules such as leaves and reproductive organs undergo senescence, the plant as a whole may display extraordinary longevity, enabled by its modular architecture and perpetually active meristems. This review explores aging and senescence in plants by challenging commonly held assumptions and integrating emerging insights from telomere biology and epigenetic regulation. We critically examine the role of telomere length as a determinant of replicative lifespan, arguing that its importance is often overstated, particularly in the context of plant systems where telomerase activity persists in meristematic tissues. In contrast, the epigenetic landscape-including DNA methylation, histone modifications, chromatin remodeling, and non-coding RNAs-plays a dynamic and increasingly appreciated role in orchestrating senescence at cellular and organ levels. We synthesize current understanding of how these chromatin-level mechanisms interact with developmental cues and environmental stresses to regulate genome stability, transcriptional reprogramming, and longevity. By integrating chromosomal and epigenetic processes, this review provides a refined conceptual framework for understanding plant aging and highlights new opportunities to enhance resilience and lifespan in crops and long-lived species through targeted manipulation of telomere maintenance and epigenetic pathways.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10611 - Plant sciences, botany

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Cellular and Molecular Life Sciences

ISSN

1420-682X

e-ISSN

1420-9071

Svazek periodika

82

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

18

Strana od-do

1-18

Kód UT WoS článku

001604740400003

EID výsledku v databázi Scopus

2-s2.0-105020258445