Vztah mezi homocysteinem a cysteinem u pacientů s různými angiografickými nálezy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F07%3A00006515" target="_blank" >RIV/00216275:25310/07:00006515 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The relationship between homocysteine and cysteine in patients with different angiographic findings

Popis výsledku v původním jazyce

Background. We studied the relation between plasma total homocysteine and cysteine levels in men with positive and negative angiographic findings. The negative finding was defined as no stenosis in coronary arteries. The positive result was characterizedas 70% or more stenosis in coronary arteries or as 50% or more stenosis in arteria coronaria sinistra. Methods. The degree of stenosis was determined by coronary angiography. Both of analytes were measured simultaneously using ion-paired HPLC method with coulometric detection. Results. We compared this method with HPLC method with fluorescence detection by linear regression: HPLC/ED = 1.1435 (HPLC/FD) ? 0.273 umol/l, R2 = 0.9945 for homocysteine and HPLC/ED = 0.8737 (HPLC/FD) + 56.534 umol/l, R2 = 0.8564 for cysteine. The significant positive correlation between levels of cysteine and homocysteine was found in the angiographically negative group (r = 0.506, p = 0.044). In contrast to this finding, there was no significantly correlation

Název v anglickém jazyce

The relationship between homocysteine and cysteine in patients with different angiographic findings

Popis výsledku anglicky

Background. We studied the relation between plasma total homocysteine and cysteine levels in men with positive and negative angiographic findings. The negative finding was defined as no stenosis in coronary arteries. The positive result was characterizedas 70% or more stenosis in coronary arteries or as 50% or more stenosis in arteria coronaria sinistra. Methods. The degree of stenosis was determined by coronary angiography. Both of analytes were measured simultaneously using ion-paired HPLC method with coulometric detection. Results. We compared this method with HPLC method with fluorescence detection by linear regression: HPLC/ED = 1.1435 (HPLC/FD) ? 0.273 umol/l, R2 = 0.9945 for homocysteine and HPLC/ED = 0.8737 (HPLC/FD) + 56.534 umol/l, R2 = 0.8564 for cysteine. The significant positive correlation between levels of cysteine and homocysteine was found in the angiographically negative group (r = 0.506, p = 0.044). In contrast to this finding, there was no significantly correlation

Druh

D - Stať ve sborníku

CEP obor

CE - Biochemie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2007

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Clinical Chemistry and Laboratory Medicine

ISBN

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ISSN

1434-6621

e-ISSN

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Počet stran výsledku

1

Strana od-do

"S250"

Název nakladatele

Walter de Gruyter GmbH & Co. KG

Místo vydání

Berlin

Místo konání akce

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Datum konání akce

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Typ akce podle státní příslušnosti

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Kód UT WoS článku

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