Influence of Cu(II) Ions on the Mechanism of the Ring Transformation of S-(2-Oxotetrahydrofuran-3-yl)-N-(4-methoxyphenyl)isothiouronium Bromide

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F13%3A39896103" target="_blank" >RIV/00216275:25310/13:39896103 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1002/kin.20761" target="_blank" >http://dx.doi.org/10.1002/kin.20761</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/kin.20761" target="_blank" >10.1002/kin.20761</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Influence of Cu(II) Ions on the Mechanism of the Ring Transformation of S-(2-Oxotetrahydrofuran-3-yl)-N-(4-methoxyphenyl)isothiouronium Bromide

Popis výsledku v původním jazyce

The effect of additional Cu(II) ions on the rate of transformation of S-(2-oxotetrahydrofuran-3-yl)-N-(4-methoxyphenyl)isothiouronium bromide (1) into 5-(2-hydroxyethyl)-2-[(4-methoxyphenyl)imino]-1,3-thiazolidin-4-one (2) has been studied in aqueous buffer solutions. The reaction acceleration in acetate buffers is caused by the formation of a relatively weakly bonded complex (Kc = 600 L center dot mol1) of substrate with copper(II) acetate in which the Cu(II) ion acts as a Lewis acid coordinating the carbonyl oxygen and facilitating the intramolecular attack, leading to the formation of intermediate T +/-. The formation of the complex of copper(II) acetate with free isothiourea in the fast preequilibrium (Kc) is followed by the rate-limiting transformation (kCu) of this complex. At the high concentrations of the acetate anions, the reaction is retarded by the competitive reaction of these ions with copper(II) acetate to give an unreactive complex [Cu(OAc)4]2. The influence of Cu(II) i

Název v anglickém jazyce

Influence of Cu(II) Ions on the Mechanism of the Ring Transformation of S-(2-Oxotetrahydrofuran-3-yl)-N-(4-methoxyphenyl)isothiouronium Bromide

Popis výsledku anglicky

The effect of additional Cu(II) ions on the rate of transformation of S-(2-oxotetrahydrofuran-3-yl)-N-(4-methoxyphenyl)isothiouronium bromide (1) into 5-(2-hydroxyethyl)-2-[(4-methoxyphenyl)imino]-1,3-thiazolidin-4-one (2) has been studied in aqueous buffer solutions. The reaction acceleration in acetate buffers is caused by the formation of a relatively weakly bonded complex (Kc = 600 L center dot mol1) of substrate with copper(II) acetate in which the Cu(II) ion acts as a Lewis acid coordinating the carbonyl oxygen and facilitating the intramolecular attack, leading to the formation of intermediate T +/-. The formation of the complex of copper(II) acetate with free isothiourea in the fast preequilibrium (Kc) is followed by the rate-limiting transformation (kCu) of this complex. At the high concentrations of the acetate anions, the reaction is retarded by the competitive reaction of these ions with copper(II) acetate to give an unreactive complex [Cu(OAc)4]2. The influence of Cu(II) i

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CC - Organická chemie

OECD FORD obor

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Projekt

<a href="/cs/project/EE2.3.30.0021" target="_blank" >EE2.3.30.0021: Posílení excelentních týmů výzkumu a vývoje na Univerzitě Pardubice</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

INTERNATIONAL JOURNAL OF CHEMICAL KINETICS

ISSN

0538-8066

e-ISSN

—

Svazek periodika

45

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

248-255

Kód UT WoS článku

000315352700005

EID výsledku v databázi Scopus

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