Cross-Linker Effects on the Separation Efficiency on (Poly)methacrylate Capillary Monolithic Columns. Part II. Aqueous Normal-Phase Liquid Chromatography

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F13%3A39896311" target="_blank" >RIV/00216275:25310/13:39896311 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S0021967313004639" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0021967313004639</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.chroma.2013.03.025" target="_blank" >10.1016/j.chroma.2013.03.025</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Cross-Linker Effects on the Separation Efficiency on (Poly)methacrylate Capillary Monolithic Columns. Part II. Aqueous Normal-Phase Liquid Chromatography

Popis výsledku v původním jazyce

We synthesized seven different polymethacrylate monolithic capillary columns using N,N-dimethyl-N-metacryloxyethyl-N-(3-sulfopropyl) ammonium betaine functional monomer (MEDSA) and various cross-linking monomers differing in the polarity and size. The efficiency of monolithic columns for polar low-molecular compounds in the aqueous normal-phase (HILIC) mode depends rather on the polarity, than on the size of the cross-linker molecules. Cross-linking molecules, which exhibit high polarity can produce poly(methacrylate) monoliths with an increase in pore sizes below 50 nm. Columns prepared with pentaerythritol triacrylate or bisphenol A dimethacrylate cross-linkers show large inner pore (mesopore) porosity, and provide poor efficiency, whereas columns with trioxyethylene dimethacrylate (TriEDMA) and tetraoxyethylene dimethacrylate (TeEDMA) cross-linkers showed poor permeability. Columns prepared using dioxyethylene dimethacrylate (DiEDMA), and especially glycerolate dimethacrylate (BIGDM

Název v anglickém jazyce

Cross-Linker Effects on the Separation Efficiency on (Poly)methacrylate Capillary Monolithic Columns. Part II. Aqueous Normal-Phase Liquid Chromatography

Popis výsledku anglicky

We synthesized seven different polymethacrylate monolithic capillary columns using N,N-dimethyl-N-metacryloxyethyl-N-(3-sulfopropyl) ammonium betaine functional monomer (MEDSA) and various cross-linking monomers differing in the polarity and size. The efficiency of monolithic columns for polar low-molecular compounds in the aqueous normal-phase (HILIC) mode depends rather on the polarity, than on the size of the cross-linker molecules. Cross-linking molecules, which exhibit high polarity can produce poly(methacrylate) monoliths with an increase in pore sizes below 50 nm. Columns prepared with pentaerythritol triacrylate or bisphenol A dimethacrylate cross-linkers show large inner pore (mesopore) porosity, and provide poor efficiency, whereas columns with trioxyethylene dimethacrylate (TriEDMA) and tetraoxyethylene dimethacrylate (TeEDMA) cross-linkers showed poor permeability. Columns prepared using dioxyethylene dimethacrylate (DiEDMA), and especially glycerolate dimethacrylate (BIGDM

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

<a href="/cs/project/GAP206%2F12%2F0398" target="_blank" >GAP206/12/0398: Dvourozměrné separace v kapalných médiích</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Chromatography A

ISSN

0021-9673

e-ISSN

—

Svazek periodika

1289

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

11

Strana od-do

47-57

Kód UT WoS článku

000317881800006

EID výsledku v databázi Scopus

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