Lipidomic differentiation of breast cancer tissues and surrounding normal tissues using HILIC-HPLC/ESI-MS

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F14%3A39899351" target="_blank" >RIV/00216275:25310/14:39899351 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Lipidomic differentiation of breast cancer tissues and surrounding normal tissues using HILIC-HPLC/ESI-MS

Popis výsledku v původním jazyce

Breast cancer is the most common malignant tumor in women population and one of the most common causes of cancer death. The lipid metabolism plays an important role in the oxidative stress and is associated with factors linked to the breast cancer risk including the hormonal balance, body mass index, breast density, drug metabolism, growth of insulin levels, etc. The coupling of high-performance liquid chromatography and mass spectrometry (HPLC/MS) is the most frequently used technique for highly sensitive and selective lipidomic characterization with the possibility to identify and quantify complex mixtures of lipids. The main challenge in the lipidomic studies of biological samples is the statistical evaluation of complex data sets.

Název v anglickém jazyce

Lipidomic differentiation of breast cancer tissues and surrounding normal tissues using HILIC-HPLC/ESI-MS

Popis výsledku anglicky

Breast cancer is the most common malignant tumor in women population and one of the most common causes of cancer death. The lipid metabolism plays an important role in the oxidative stress and is associated with factors linked to the breast cancer risk including the hormonal balance, body mass index, breast density, drug metabolism, growth of insulin levels, etc. The coupling of high-performance liquid chromatography and mass spectrometry (HPLC/MS) is the most frequently used technique for highly sensitive and selective lipidomic characterization with the possibility to identify and quantify complex mixtures of lipids. The main challenge in the lipidomic studies of biological samples is the statistical evaluation of complex data sets.

Druh

O - Ostatní výsledky

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů