Omega-3 fatty acid supplementation candidates can be selected using fatty acid profiling

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F15%3A39900764" target="_blank" >RIV/00216275:25310/15:39900764 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1002/ejlt.201400213" target="_blank" >http://dx.doi.org/10.1002/ejlt.201400213</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/ejlt.201400213" target="_blank" >10.1002/ejlt.201400213</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Omega-3 fatty acid supplementation candidates can be selected using fatty acid profiling

Popis výsledku v původním jazyce

The aim of this study was to evaluate the fatty acid(FA) profile in the plasma and erythrocyte membranes of apparently healthy men compared to male patients with various cardiovascular diseases (CVD). The plasma FA profiles were analyzed in five groups of subjects aged 37-57 years: groups 1 and 2 were male voluntary blood donors with a body mass index(BMI) 25.1 +/- 1.6,(Group1, N = 12) and a BMI 32.9 +/- 4.5, (Group 2, N = 11) respectively, male patients with chronic heart failure due to dilated cardiomyopathy (Group 3, N = 10), chronic atrial fibrillation without heart failure or coronary heart disease (Group 4, N = 10) and patients after myocardial infarction (Group 5, N = 11). The FA profile in plasma and erythrocytes was measured by gas chromatography (GC) with flame ionization detection and basic plasma lipid parameters were then estimated. Deficiencies of eicosapentaenoic acid and docosahexaenoic acid were found in all the groups of CVD patients and in Group 2 (BMI 32.9 +/- 4.5)

Název v anglickém jazyce

Omega-3 fatty acid supplementation candidates can be selected using fatty acid profiling

Popis výsledku anglicky

The aim of this study was to evaluate the fatty acid(FA) profile in the plasma and erythrocyte membranes of apparently healthy men compared to male patients with various cardiovascular diseases (CVD). The plasma FA profiles were analyzed in five groups of subjects aged 37-57 years: groups 1 and 2 were male voluntary blood donors with a body mass index(BMI) 25.1 +/- 1.6,(Group1, N = 12) and a BMI 32.9 +/- 4.5, (Group 2, N = 11) respectively, male patients with chronic heart failure due to dilated cardiomyopathy (Group 3, N = 10), chronic atrial fibrillation without heart failure or coronary heart disease (Group 4, N = 10) and patients after myocardial infarction (Group 5, N = 11). The FA profile in plasma and erythrocytes was measured by gas chromatography (GC) with flame ionization detection and basic plasma lipid parameters were then estimated. Deficiencies of eicosapentaenoic acid and docosahexaenoic acid were found in all the groups of CVD patients and in Group 2 (BMI 32.9 +/- 4.5)

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

<a href="/cs/project/GAP206%2F11%2F0022" target="_blank" >GAP206/11/0022: Lipidomický profil pacientů s kardiovaskulárními chorobami</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European Journal of Lipid Science and Technology

ISSN

1438-7697

e-ISSN

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Svazek periodika

117

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

7

Strana od-do

601-607

Kód UT WoS článku

000354269400004

EID výsledku v databázi Scopus

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