The ratio of oxidized and reduced forms of selected antioxidants as a possible marker of oxidative stress in humans

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F16%3A39901832" target="_blank" >RIV/00216275:25310/16:39901832 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1002/bmc.3529" target="_blank" >http://dx.doi.org/10.1002/bmc.3529</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/bmc.3529" target="_blank" >10.1002/bmc.3529</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The ratio of oxidized and reduced forms of selected antioxidants as a possible marker of oxidative stress in humans

Popis výsledku v původním jazyce

Oxidative stress is an imbalance between reactive oxygen species exposure and the ability of organisms to detoxify the reactive intermediates and to repair the oxidative damage of biologically important molecules. Many clinical studies of oxidative stress unfortunately provide conflicting and contradictory results. The ability of antioxidant systems to adequately respond to oxidative stress can be used in laboratory diagnostics. In the present review, methods using the ratio of reduced and oxidized forms of uric acid, ascorbic acid, glutathione and coenzyme Q10 as suitable indicators of oxidative stress are discussed. From the mentioned publications it is evident that suitable sample preparation prior to analysis is crucial.

Název v anglickém jazyce

The ratio of oxidized and reduced forms of selected antioxidants as a possible marker of oxidative stress in humans

Popis výsledku anglicky

Oxidative stress is an imbalance between reactive oxygen species exposure and the ability of organisms to detoxify the reactive intermediates and to repair the oxidative damage of biologically important molecules. Many clinical studies of oxidative stress unfortunately provide conflicting and contradictory results. The ability of antioxidant systems to adequately respond to oxidative stress can be used in laboratory diagnostics. In the present review, methods using the ratio of reduced and oxidized forms of uric acid, ascorbic acid, glutathione and coenzyme Q10 as suitable indicators of oxidative stress are discussed. From the mentioned publications it is evident that suitable sample preparation prior to analysis is crucial.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CE - Biochemie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomedical Chromatography

ISSN

0269-3879

e-ISSN

—

Svazek periodika

30

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

16

Strana od-do

13-28

Kód UT WoS článku

000367349800003

EID výsledku v databázi Scopus

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