Insulin resistance

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F18%3A39912925" target="_blank" >RIV/00216275:25310/18:39912925 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Insulin resistance

Popis výsledku v původním jazyce

Insulin resistance is a condition where our body is unable to optimally manage the essential nutrients. Insulin loses its efficiency, it leads to hyperglycemia and lipid metabolism is impaired. In acquired insulin resistance is all caused by obesity. The prevalence of obesity is increasing worldwide nowadays. The insulin resistance precedes diabetes mellitus type 2 and other complications associated with both diabetes and obesity. The aim of this work was to measure concentrations of monounsaturated fatty acids and to find out dependencies with insulin resistance and diabetes mellitus type 2. There were analyzed 21 samples of type 2 diabetics plasma and 17 samples of healthy donors plasma. After lipid extraction from plasma, the lipids were separated by thin layer chromatography into individual classes, derivatized and methyl esters of fatty acids were analyzed by gas chromatograph with flame-ionization detector. The largest changes were observed for stearic, oleic, trans-vaccenic and nervonic acid.

Název v anglickém jazyce

Insulin resistance

Popis výsledku anglicky

Insulin resistance is a condition where our body is unable to optimally manage the essential nutrients. Insulin loses its efficiency, it leads to hyperglycemia and lipid metabolism is impaired. In acquired insulin resistance is all caused by obesity. The prevalence of obesity is increasing worldwide nowadays. The insulin resistance precedes diabetes mellitus type 2 and other complications associated with both diabetes and obesity. The aim of this work was to measure concentrations of monounsaturated fatty acids and to find out dependencies with insulin resistance and diabetes mellitus type 2. There were analyzed 21 samples of type 2 diabetics plasma and 17 samples of healthy donors plasma. After lipid extraction from plasma, the lipids were separated by thin layer chromatography into individual classes, derivatized and methyl esters of fatty acids were analyzed by gas chromatograph with flame-ionization detector. The largest changes were observed for stearic, oleic, trans-vaccenic and nervonic acid.

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

10608 - Biochemistry and molecular biology

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Monitorování cizorodých látek v životním prostředí XX. : sborník ze semináře s mezinárodní účastí

ISBN

978-80-7560-154-4

ISSN

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e-ISSN

neuvedeno

Počet stran výsledku

10

Strana od-do

51-60

Název nakladatele

Univerzita Pardubice

Místo vydání

Pardubice

Místo konání akce

Ovčárna pod Pradědem

Datum konání akce

25. 4. 2018

Typ akce podle státní příslušnosti

EUR - Evropská akce

Kód UT WoS článku

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