Electrochemical Determination Of Dopamine And Uric Acid In Blood Serum Using Anionic Surfactants At Carbon Paste Electrodes

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F20%3A39916832" target="_blank" >RIV/00216275:25310/20:39916832 - isvavai.cz</a>

Výsledek na webu

<a href="https://mjas.analis.com.my/mjas/v24_n1/pdf/Berisha_24_1_11.pdf" target="_blank" >https://mjas.analis.com.my/mjas/v24_n1/pdf/Berisha_24_1_11.pdf</a>

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Electrochemical Determination Of Dopamine And Uric Acid In Blood Serum Using Anionic Surfactants At Carbon Paste Electrodes

Popis výsledku v původním jazyce

A selective and sensitive method was developed for the simultaneous electrochemical determination of dopamine and uric acid by using a sodium dodecylbenzenesulfonate (SDBS) and sodium dodecyl sulfate (SDS) as a surface modifier of carbon paste electrodes (CPEs). At lower concentration of SDS and SDBS they form a negatively charged monolayer on CPE surface because of surfactants’ hydrophobic chain interaction with paraffin of CPE. Optimized concentration of surfactants was 2 mM for SDS and 1 mM for SDBS in phosphate buffer solution (0.1 M, pH 7 and pH 6, respectively). Compared with plain CPE, CPE modified with SDS (CPE-SDS) and CPE modified with SDBS (CPE-SDBS) have shown the improved electrochemical response of dopamine (DA) at 0.230 V and uric acid (UA) at 0.345 V due to electrostatic interactions between positively charged analytes and surface negatively charged of SDBS and SDS. Under optimal experimental conditions, the designed electrodes exhibited a wide range of linear response to DA from 0.53 μM to 31.6 μM and UA from 5.95 μM to 118.97 μM. The detection limits for DA and UA were found to be 0.26 and 1.10 µM with CPE-SDS, whilst 0.22 and 0.38 µM with CPE-SDBS. The CPE-SDBS and CPE-SDS showed good reproducibility, repeatability, stability and high selectivity for determination of DA and UA in blood serum samples.

Název v anglickém jazyce

Electrochemical Determination Of Dopamine And Uric Acid In Blood Serum Using Anionic Surfactants At Carbon Paste Electrodes

Popis výsledku anglicky

A selective and sensitive method was developed for the simultaneous electrochemical determination of dopamine and uric acid by using a sodium dodecylbenzenesulfonate (SDBS) and sodium dodecyl sulfate (SDS) as a surface modifier of carbon paste electrodes (CPEs). At lower concentration of SDS and SDBS they form a negatively charged monolayer on CPE surface because of surfactants’ hydrophobic chain interaction with paraffin of CPE. Optimized concentration of surfactants was 2 mM for SDS and 1 mM for SDBS in phosphate buffer solution (0.1 M, pH 7 and pH 6, respectively). Compared with plain CPE, CPE modified with SDS (CPE-SDS) and CPE modified with SDBS (CPE-SDBS) have shown the improved electrochemical response of dopamine (DA) at 0.230 V and uric acid (UA) at 0.345 V due to electrostatic interactions between positively charged analytes and surface negatively charged of SDBS and SDS. Under optimal experimental conditions, the designed electrodes exhibited a wide range of linear response to DA from 0.53 μM to 31.6 μM and UA from 5.95 μM to 118.97 μM. The detection limits for DA and UA were found to be 0.26 and 1.10 µM with CPE-SDS, whilst 0.22 and 0.38 µM with CPE-SDBS. The CPE-SDBS and CPE-SDS showed good reproducibility, repeatability, stability and high selectivity for determination of DA and UA in blood serum samples.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Malaysian Journal of Analytical Sciences

ISSN

1394-2506

e-ISSN

—

Svazek periodika

24

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

MY - Malajsie

Počet stran výsledku

10

Strana od-do

97-106

Kód UT WoS článku

—

EID výsledku v databázi Scopus

2-s2.0-85079715474