Olfactory dysfunction following herpetic meningoencephalitis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25520%2F10%3A39882887" target="_blank" >RIV/00216275:25520/10:39882887 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Olfactory dysfunction following herpetic meningoencephalitis

Popis výsledku v původním jazyce

Herpetic meningoencephalitis (HME) is a rare but often lethal herpes simplex infection. Patients who survive generally retain neurological deficits. Little information is available on degree and recovery of olfactory impairment following HME. In this retrospective case series, three patients (two women, one man) who had survived HME were tested with standardized olfactory tests (Sniffin' Sticks). In conclusion, the present findings show that olfactory function is often permanently damaged in patients who have had HME. Lesions lead to various patterns of olfactory loss. Together with histological and clinical data from the literature this suggests further that the olfactory pathway plays a major role in the spread of herpetic meningoencephalitis. It also raises the question whether the olfactory epithelium serves as an entry into the brain for other pathogens.

Název v anglickém jazyce

Olfactory dysfunction following herpetic meningoencephalitis

Popis výsledku anglicky

Herpetic meningoencephalitis (HME) is a rare but often lethal herpes simplex infection. Patients who survive generally retain neurological deficits. Little information is available on degree and recovery of olfactory impairment following HME. In this retrospective case series, three patients (two women, one man) who had survived HME were tested with standardized olfactory tests (Sniffin' Sticks). In conclusion, the present findings show that olfactory function is often permanently damaged in patients who have had HME. Lesions lead to various patterns of olfactory loss. Together with histological and clinical data from the literature this suggests further that the olfactory pathway plays a major role in the spread of herpetic meningoencephalitis. It also raises the question whether the olfactory epithelium serves as an entry into the brain for other pathogens.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FF - ORL, oftalmologie, stomatologie

OECD FORD obor

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Projekt

<a href="/cs/project/1A8667" target="_blank" >1A8667: Vyšetření čichu se zaměřením na pracující v chemickém provozu</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Neurology

ISSN

0340-5354

e-ISSN

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Svazek periodika

257

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

5

Strana od-do

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Kód UT WoS článku

000275529300021

EID výsledku v databázi Scopus

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