Spontaneous spinal epidural haematoma: management and main risk factors in era of anticoagulant/antiplatelet treatment

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25520%2F21%3A39918562" target="_blank" >RIV/00216275:25520/21:39918562 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/21:43922423 RIV/00064173:_____/21:N0000025

Výsledek na webu

<a href="https://journals.viamedica.pl/neurologia_neurochirurgia_polska/article/view/PJNNS.a2021.0066/64425" target="_blank" >https://journals.viamedica.pl/neurologia_neurochirurgia_polska/article/view/PJNNS.a2021.0066/64425</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5603/PJNNS.a2021.0066" target="_blank" >10.5603/PJNNS.a2021.0066</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Spontaneous spinal epidural haematoma: management and main risk factors in era of anticoagulant/antiplatelet treatment

Popis výsledku v původním jazyce

Aim of the study. Spontaneous spinal epidural haematomas (SSEH) are rare nosological units wherein acute collections of blood develop in the spinal canal. SSEH are usually manifested by sudden severe back pain accompanied by the development of neurological symptoms. In this study, we retrospectively describe management and the main risk factors of SSEH in a series of 14 cases. Material and methods. Between 2010 and 2019, we examined 14 patients (age range 17-89 years, 10 women) diagnosed with SSEH. Eight cases were patients using anticoagulant therapies (six warfarin, one dabigatran, one apixaban) and two others were using ASA of 100 mg/day. The exact localisation and extent of changes was determined from acute magnetic resonance imaging. Three people using warfarin had INR values higher than 3.0 at the time of their diagnosis. Results. Ten patients (71%) were taking oral anticoagulants or a ntiplatelet agents. In seven patients, SSEH were localised in the lower cervical/thoracic spine. Ten patients (71%) had arterial hypertension. Six patients underwent acute surgery due to rapidly developing spinal cord compression. Eight patients (57%) with slight or mild neurological symptoms were successfully managed without surgery. Conclusions. SSEH should be suspected in any patient receiving anticoagulant/anti platelet agents who complains of sudden, severe back pain accompanied by neurological symptoms. SSEH is mostly localised in the lower cervical/thoracic spine. Arterial hypertension appears to be a risk factor of SSEH. Early decompression is an important therapeutic approach; in cases with minor neurological deficits, conservative treatment may be chosen.

Název v anglickém jazyce

Spontaneous spinal epidural haematoma: management and main risk factors in era of anticoagulant/antiplatelet treatment

Popis výsledku anglicky

Aim of the study. Spontaneous spinal epidural haematomas (SSEH) are rare nosological units wherein acute collections of blood develop in the spinal canal. SSEH are usually manifested by sudden severe back pain accompanied by the development of neurological symptoms. In this study, we retrospectively describe management and the main risk factors of SSEH in a series of 14 cases. Material and methods. Between 2010 and 2019, we examined 14 patients (age range 17-89 years, 10 women) diagnosed with SSEH. Eight cases were patients using anticoagulant therapies (six warfarin, one dabigatran, one apixaban) and two others were using ASA of 100 mg/day. The exact localisation and extent of changes was determined from acute magnetic resonance imaging. Three people using warfarin had INR values higher than 3.0 at the time of their diagnosis. Results. Ten patients (71%) were taking oral anticoagulants or a ntiplatelet agents. In seven patients, SSEH were localised in the lower cervical/thoracic spine. Ten patients (71%) had arterial hypertension. Six patients underwent acute surgery due to rapidly developing spinal cord compression. Eight patients (57%) with slight or mild neurological symptoms were successfully managed without surgery. Conclusions. SSEH should be suspected in any patient receiving anticoagulant/anti platelet agents who complains of sudden, severe back pain accompanied by neurological symptoms. SSEH is mostly localised in the lower cervical/thoracic spine. Arterial hypertension appears to be a risk factor of SSEH. Early decompression is an important therapeutic approach; in cases with minor neurological deficits, conservative treatment may be chosen.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30210 - Clinical neurology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Neurologia i Neurochirurgia Polska

ISSN

0028-3843

e-ISSN

—

Svazek periodika

55

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

8

Strana od-do

574-581

Kód UT WoS článku

000744178100010

EID výsledku v databázi Scopus

2-s2.0-85122213512