Deposition of glass fibers in a physically realistic replica of the human respiratory tract

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F17%3APU126100" target="_blank" >RIV/00216305:26210/17:PU126100 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0021850217300435" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0021850217300435</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jaerosci.2017.11.006" target="_blank" >10.1016/j.jaerosci.2017.11.006</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Deposition of glass fibers in a physically realistic replica of the human respiratory tract

Popis výsledku v původním jazyce

Regional deposition of glass fibers was investigated in a physically realistic, human respiratory tract replica. The replica begins with the oral cavity and includes the airways up to the 7th generation of the tracheobronchial tree. Uniform diameter glass fibers were classified by length using a dielectrophoretic classifier and introduced into the replica at three steady-state flow rates (15, 30, and 50 LPM). A novel automatic image processing method was utilized to speed up the sample analysis and make it more reproducible. Fractional deposition was high in the oral cavity and the upper respiratory airways. Deposition density was higher in the first few generations of the tracheobronchial tree. Deposition efficiencies were compared with published data and good agreement was obtained. Our data confirmed that the deposition efficiency increased with increasing Stokes number indicating that impaction was the main deposition mechanism. The experimental data were used to propose new empirical models predicting fiber deposition in the tracheobronchial tree.

Název v anglickém jazyce

Deposition of glass fibers in a physically realistic replica of the human respiratory tract

Popis výsledku anglicky

Regional deposition of glass fibers was investigated in a physically realistic, human respiratory tract replica. The replica begins with the oral cavity and includes the airways up to the 7th generation of the tracheobronchial tree. Uniform diameter glass fibers were classified by length using a dielectrophoretic classifier and introduced into the replica at three steady-state flow rates (15, 30, and 50 LPM). A novel automatic image processing method was utilized to speed up the sample analysis and make it more reproducible. Fractional deposition was high in the oral cavity and the upper respiratory airways. Deposition density was higher in the first few generations of the tracheobronchial tree. Deposition efficiencies were compared with published data and good agreement was obtained. Our data confirmed that the deposition efficiency increased with increasing Stokes number indicating that impaction was the main deposition mechanism. The experimental data were used to propose new empirical models predicting fiber deposition in the tracheobronchial tree.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20301 - Mechanical engineering

Projekt

<a href="/cs/project/GA16-23675S" target="_blank" >GA16-23675S: Vícerozměrné laminární, přechodné a turbulentní urychlující a zpomalující proudění v lidském dýchacím traktu s transportem a depozicí aerosolů</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

JOURNAL OF AEROSOL SCIENCE

ISSN

0021-8502

e-ISSN

1879-1964

Svazek periodika

neuveden

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

15

Strana od-do

1-15

Kód UT WoS článku

000424348000014

EID výsledku v databázi Scopus

2-s2.0-85038877559