Experimental and computational modelling of flow of fibres in human airways
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F19%3APU132484" target="_blank" >RIV/00216305:26210/19:PU132484 - isvavai.cz</a>
Výsledek na webu
<a href="https://www.liebertpub.com/doi/full/10.1089/jamp.2019.ab02.abstracts" target="_blank" >https://www.liebertpub.com/doi/full/10.1089/jamp.2019.ab02.abstracts</a>
DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Experimental and computational modelling of flow of fibres in human airways
Popis výsledku v původním jazyce
The ability of fibres to align with the flow has been identified as a reason for higher penetration of fibres into the lungs compared to spherical particles by many studies. However, prediction of the fate of inhaled fibres by computational methods is complicated due to the necessary mathematical apparatus and the lack of experimental data for validation. It is common to apply coefficients accounting for the preferential orientation of the fibre flowing through the airways. A new experimental rig has been built to visualize the flow of micron-sized fibres and record the angles of their rotation upstream and downstream of a single bifurcation. The recorded angles are statistically analysed and improved coefficients of fibre orientation will be calculated. The experimental rig consists of a dielectrophoretic classifier of fibres, the model of human trachea and first bronchi, a breathing simulator and a high-speed camera with appropriate illumination. These experiments are supplemented with computational
Název v anglickém jazyce
Experimental and computational modelling of flow of fibres in human airways
Popis výsledku anglicky
The ability of fibres to align with the flow has been identified as a reason for higher penetration of fibres into the lungs compared to spherical particles by many studies. However, prediction of the fate of inhaled fibres by computational methods is complicated due to the necessary mathematical apparatus and the lack of experimental data for validation. It is common to apply coefficients accounting for the preferential orientation of the fibre flowing through the airways. A new experimental rig has been built to visualize the flow of micron-sized fibres and record the angles of their rotation upstream and downstream of a single bifurcation. The recorded angles are statistically analysed and improved coefficients of fibre orientation will be calculated. The experimental rig consists of a dielectrophoretic classifier of fibres, the model of human trachea and first bronchi, a breathing simulator and a high-speed camera with appropriate illumination. These experiments are supplemented with computational
Klasifikace
Druh
O - Ostatní výsledky
CEP obor
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OECD FORD obor
20301 - Mechanical engineering
Návaznosti výsledku
Projekt
<a href="/cs/project/GA18-25618S" target="_blank" >GA18-25618S: Výzkum účinku nestacionárního proudění na transport vláken v postupně se větvících minikanálech</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2019
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů