On the behavior of inhaled fibers in a replica of the first airway bifurcation under steady flow conditions

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F22%3APU143782" target="_blank" >RIV/00216305:26210/22:PU143782 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.tandfonline.com/doi/full/10.1080/02786826.2022.2027334" target="_blank" >https://www.tandfonline.com/doi/full/10.1080/02786826.2022.2027334</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/02786826.2022.2027334" target="_blank" >10.1080/02786826.2022.2027334</a>

Jazyk výsledku

angličtina

Název v původním jazyce

On the behavior of inhaled fibers in a replica of the first airway bifurcation under steady flow conditions

Popis výsledku v původním jazyce

Inhaled fibers can potentially cause inflammation of the lung tissue and interstitium, which after long-term exposure may lead to lung cancer, malignant mesothelioma, or pulmonary and pleural fibrosis. To reduce the risk and set the appropriate occupational hygiene regulations, it is important to be able to precisely calculate the fate of inhaled fibers depending on their physical characteristics and inhalation conditions. In the absence of experimental data on the real behavior - trajectories, orientation and flipping - of inhaled fibers, a new test rig was assembled for visualization and recording of flowing fibers in a replica of the human trachea and the first bronchial bifurcation. Fibers prepared from commercially produced glass fibers have been processed, dispersed, and introduced into the airway replica. Visualization was performed using a powerful LED light and a high-speed camera. The flow of fibers was evaluated upstream and downstream of the realistic asymmetrical bifurcation and dependence on flow conditions was sought. The fractions of parallelly and perpendicularly flowing fibers were statistically evaluated in three locations. The frequency of flipping was also analyzed. The results show that the parallel orientation of the fibers is less dominant than expected. The fiber orientation tables for various conditions can be used to adjust and improve computational simulations of inhaled fibers in the human airways.

Název v anglickém jazyce

On the behavior of inhaled fibers in a replica of the first airway bifurcation under steady flow conditions

Popis výsledku anglicky

Inhaled fibers can potentially cause inflammation of the lung tissue and interstitium, which after long-term exposure may lead to lung cancer, malignant mesothelioma, or pulmonary and pleural fibrosis. To reduce the risk and set the appropriate occupational hygiene regulations, it is important to be able to precisely calculate the fate of inhaled fibers depending on their physical characteristics and inhalation conditions. In the absence of experimental data on the real behavior - trajectories, orientation and flipping - of inhaled fibers, a new test rig was assembled for visualization and recording of flowing fibers in a replica of the human trachea and the first bronchial bifurcation. Fibers prepared from commercially produced glass fibers have been processed, dispersed, and introduced into the airway replica. Visualization was performed using a powerful LED light and a high-speed camera. The flow of fibers was evaluated upstream and downstream of the realistic asymmetrical bifurcation and dependence on flow conditions was sought. The fractions of parallelly and perpendicularly flowing fibers were statistically evaluated in three locations. The frequency of flipping was also analyzed. The results show that the parallel orientation of the fibers is less dominant than expected. The fiber orientation tables for various conditions can be used to adjust and improve computational simulations of inhaled fibers in the human airways.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20301 - Mechanical engineering

Projekt

<a href="/cs/project/GA18-25618S" target="_blank" >GA18-25618S: Výzkum účinku nestacionárního proudění na transport vláken v postupně se větvících minikanálech</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

AEROSOL SCIENCE AND TECHNOLOGY

ISSN

0278-6826

e-ISSN

1521-7388

Svazek periodika

56

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

15

Strana od-do

367-381

Kód UT WoS článku

000750493000001

EID výsledku v databázi Scopus

2-s2.0-85124132709