Numerical Study of Flow Field Characteristics in the Trachea During Growth of Human Upper Airways

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F22%3APU146676" target="_blank" >RIV/00216305:26210/22:PU146676 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.matec-conferences.org/articles/matecconf/abs/2022/16/matecconf_aenmmte2022_01006/matecconf_aenmmte2022_01006.html" target="_blank" >https://www.matec-conferences.org/articles/matecconf/abs/2022/16/matecconf_aenmmte2022_01006/matecconf_aenmmte2022_01006.html</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1051/matecconf/202236901006" target="_blank" >10.1051/matecconf/202236901006</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Numerical Study of Flow Field Characteristics in the Trachea During Growth of Human Upper Airways

Popis výsledku v původním jazyce

The development of organs in the human body does not end at birth. During the first five years of life, changes occur in the respiratory tract, not only in terms of its dimensions but also in the way it is used. Efforts to provide non-invasive treatment in the form of medical aerosols administered to children´s lungs during this period must be supported by knowledge of the flow pattern that significantly influences their transport and deposition. Research related to flow patterns in the adult human respiratory tract is quite widespread and the phenomena that occur during inhalation in different parts of the respiratory tract have been widely documented. In the case of the paediatric respiratory tract, research is relatively scarce due to the age of the patient and the desire to minimise interference with the paediatric organism. At the Brno University of Technology, we have the geometry of the airway of a ten-month-old infant, a scaled model of an adult to match the geometry of a five-year-old child based on scientific knowledge and also an adult model of the human respiratory tract. These geometries, together with knowledge of respiratory physiology were used to compare the changes in airflow behaviour that occur in the trachea during the first five years and compare it to fully developed adult human geometry. Computational Fluid Dynamics was used to investigate the model using a Large Eddy Simulation approach. The periods of life captured by the geometries differ not only in their dimensional difference but also in their approach to airway use. The impact of these differences has been captured in the paper.

Název v anglickém jazyce

Numerical Study of Flow Field Characteristics in the Trachea During Growth of Human Upper Airways

Popis výsledku anglicky

The development of organs in the human body does not end at birth. During the first five years of life, changes occur in the respiratory tract, not only in terms of its dimensions but also in the way it is used. Efforts to provide non-invasive treatment in the form of medical aerosols administered to children´s lungs during this period must be supported by knowledge of the flow pattern that significantly influences their transport and deposition. Research related to flow patterns in the adult human respiratory tract is quite widespread and the phenomena that occur during inhalation in different parts of the respiratory tract have been widely documented. In the case of the paediatric respiratory tract, research is relatively scarce due to the age of the patient and the desire to minimise interference with the paediatric organism. At the Brno University of Technology, we have the geometry of the airway of a ten-month-old infant, a scaled model of an adult to match the geometry of a five-year-old child based on scientific knowledge and also an adult model of the human respiratory tract. These geometries, together with knowledge of respiratory physiology were used to compare the changes in airflow behaviour that occur in the trachea during the first five years and compare it to fully developed adult human geometry. Computational Fluid Dynamics was used to investigate the model using a Large Eddy Simulation approach. The periods of life captured by the geometries differ not only in their dimensional difference but also in their approach to airway use. The impact of these differences has been captured in the paper.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

20302 - Applied mechanics

Projekt

<a href="/cs/project/GA20-27653S" target="_blank" >GA20-27653S: Vliv vývoje plic u novorozenců a dětí na charakteristiky proudění a depozici aerosolů – výpočtové modelování a experimentální validace</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

2261-236X

ISBN

—

ISSN

2261-236X

e-ISSN

—

Počet stran výsledku

7

Strana od-do

1-7

Název nakladatele

EDP Sciences

Místo vydání

Piešťany

Místo konání akce

Piešťany

Datum konání akce

12. 9. 2022

Typ akce podle státní příslušnosti

EUR - Evropská akce

Kód UT WoS článku

—