Heat Generation in Biological Tissues during Photodynamic Therapy combined with Gold Nanoparticles

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F12%3APU98221" target="_blank" >RIV/00216305:26220/12:PU98221 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

čeština

Název v původním jazyce

Heat Generation in Biological Tissues during Photodynamic Therapy combined with Gold Nanoparticles

Popis výsledku v původním jazyce

One of the emerging strategies to overcome the actual drawbacks in Photodynamic Therapy is its combination with nanoparticles. Specifically, the administration of gold nanoparticles to the pathological tissue causes an increase in the optical radiation absorption that could lead to induce thermal damage in the target tissue. However, photodynamic therapy is based on photochemical interactions and therefore it is necessary to study possible thermal interactions that might occur in the target tissue due to the administration of nanoparticles. In this work we present a thermal model that tries to predict the effect of gold nanoparticles in the local heating for three different types of malignant skin tumors subjected to typical power densities applied inphotodynamic therapy. The results obtained show a negligible increase in the local temperature that demonstrates the absence of thermal damage under the irradiation conditions commonly applied in photodynamic therapy clinical practice.

Název v anglickém jazyce

Heat Generation in Biological Tissues during Photodynamic Therapy combined with Gold Nanoparticles

Popis výsledku anglicky

One of the emerging strategies to overcome the actual drawbacks in Photodynamic Therapy is its combination with nanoparticles. Specifically, the administration of gold nanoparticles to the pathological tissue causes an increase in the optical radiation absorption that could lead to induce thermal damage in the target tissue. However, photodynamic therapy is based on photochemical interactions and therefore it is necessary to study possible thermal interactions that might occur in the target tissue due to the administration of nanoparticles. In this work we present a thermal model that tries to predict the effect of gold nanoparticles in the local heating for three different types of malignant skin tumors subjected to typical power densities applied inphotodynamic therapy. The results obtained show a negligible increase in the local temperature that demonstrates the absence of thermal damage under the irradiation conditions commonly applied in photodynamic therapy clinical practice.

Druh

D - Stať ve sborníku

CEP obor

JA - Elektronika a optoelektronika, elektrotechnika

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Proceedings of 22nd International Conference Radioelektronika 2012

ISBN

978-80-214-4468-3

ISSN

—

e-ISSN

—

Počet stran výsledku

4

Strana od-do

183-186

Název nakladatele

Neuveden

Místo vydání

Neuveden

Místo konání akce

Brno

Datum konání akce

17. 4. 2012

Typ akce podle státní příslušnosti

EUR - Evropská akce

Kód UT WoS článku

—