Contributions of basic, preclinical and clinical research to the application of induced electrical currents in the indications of rehabilitation and physical medicine

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F19%3APU144150" target="_blank" >RIV/00216305:26220/19:PU144150 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.prolekare.cz/casopisy/rehabilitace-fyzikalni-lekarstvi/2019-4-25/prinosy-zakladniho-preklinickeho-a-klinickeho-vyzkumu-k-uplatneni-indukovanych-elektrickych-proudu-v-indikacich-rehabilitacni-a-fyzikalni-mediciny-122203" target="_blank" >https://www.prolekare.cz/casopisy/rehabilitace-fyzikalni-lekarstvi/2019-4-25/prinosy-zakladniho-preklinickeho-a-klinickeho-vyzkumu-k-uplatneni-indukovanych-elektrickych-proudu-v-indikacich-rehabilitacni-a-fyzikalni-mediciny-122203</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Contributions of basic, preclinical and clinical research to the application of induced electrical currents in the indications of rehabilitation and physical medicine

Popis výsledku v původním jazyce

The application of induced electric currents is increasingly used in contemporary rehabilitation and physical medicine. The induced electric currents are generated by a time-varying magnetic field and are apparently the only or at least a major biologi-cally active factor in the action of low-frequency electromagnetic fields. In addition to the “classical” pulse magnetotherapy, which provides the smallest densities of induced electric currents (usually thou-sandths to hundredths of A/m2), so-called distance or non-contact electrotherapy is increasingly popu-lar, but rather known under the names contactless electrotherapy, electrodeless therapy, inductively coupled electromagnetic field therapy, high-induction electromagnetic field therapy, etc., which typically operates at higher current densities of pulse-induced electrical currents in the order of tenths to A/m2. High-induction magnetic stimulation with perceptual and muscular motor effects, which provides current density of tens to hundreds of A/m2 in treated tissues, is also a significant development. In this work, we first investigated the effect of induced electric currents on sensory neurons responsible for the transmission of stimuli of various modalities, including those associated with nociception. In these cells, bradykinin modeled inflammation accompanied by increased calcium ion concentration in the intracellular space. We have demonstrated the influence of distance electrotherapy and high induction magnetic stimulation on the reduction of calcium concentration in the cell as well as on the slower onset and decrease of bradykinin-induced calcium wave. However, induced electrical current pulses produced by high induction magnetic stimulation increased spontaneous neuro-neuro-nal activity of primary afferent sensory cells without the presence of bradykinin inflammatory mediator. Further research was focused on the study of the behavior of endothelial cells, important in terms of angiogenesis, under the in

Název v anglickém jazyce

Contributions of basic, preclinical and clinical research to the application of induced electrical currents in the indications of rehabilitation and physical medicine

Popis výsledku anglicky

The application of induced electric currents is increasingly used in contemporary rehabilitation and physical medicine. The induced electric currents are generated by a time-varying magnetic field and are apparently the only or at least a major biologi-cally active factor in the action of low-frequency electromagnetic fields. In addition to the “classical” pulse magnetotherapy, which provides the smallest densities of induced electric currents (usually thou-sandths to hundredths of A/m2), so-called distance or non-contact electrotherapy is increasingly popu-lar, but rather known under the names contactless electrotherapy, electrodeless therapy, inductively coupled electromagnetic field therapy, high-induction electromagnetic field therapy, etc., which typically operates at higher current densities of pulse-induced electrical currents in the order of tenths to A/m2. High-induction magnetic stimulation with perceptual and muscular motor effects, which provides current density of tens to hundreds of A/m2 in treated tissues, is also a significant development. In this work, we first investigated the effect of induced electric currents on sensory neurons responsible for the transmission of stimuli of various modalities, including those associated with nociception. In these cells, bradykinin modeled inflammation accompanied by increased calcium ion concentration in the intracellular space. We have demonstrated the influence of distance electrotherapy and high induction magnetic stimulation on the reduction of calcium concentration in the cell as well as on the slower onset and decrease of bradykinin-induced calcium wave. However, induced electrical current pulses produced by high induction magnetic stimulation increased spontaneous neuro-neuro-nal activity of primary afferent sensory cells without the presence of bradykinin inflammatory mediator. Further research was focused on the study of the behavior of endothelial cells, important in terms of angiogenesis, under the in

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

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OECD FORD obor

20601 - Medical engineering

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Rehabilitace a Fyzikalni Lekarstvi

ISSN

1211-2658

e-ISSN

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Svazek periodika

2019

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

17

Strana od-do

174-190

Kód UT WoS článku

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EID výsledku v databázi Scopus

2-s2.0-85090331555