OPERON-EXPRESSER: The Innovated Gene Expression-based Algorithm for Operon Structures Inference

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F21%3APU141194" target="_blank" >RIV/00216305:26220/21:PU141194 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.fekt.vut.cz/conf/EEICT/archiv/sborniky/EEICT_2021_sbornik_1.pdf" target="_blank" >https://www.fekt.vut.cz/conf/EEICT/archiv/sborniky/EEICT_2021_sbornik_1.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

OPERON-EXPRESSER: The Innovated Gene Expression-based Algorithm for Operon Structures Inference

Popis výsledku v původním jazyce

Current biotechnological research of bacterial genomes has huge potential due to the use of next-generation sequencing (NGS) platforms. NGS era opens paths for analysis of data for sufficient description of microorganisms with ecology and biotechnology potential in the future. Although some tools for inference of specific structures in bacterial genomes exist, their pipelines and methodologies are often based only on searching bacterial genome databases and comparison with model microorganisms. This paper deals with the design of a new algorithm for operon structures inference in bacterial genomes. The algorithm combines searching in bacterial databases and gene expression information processing. The algorithm was implemented in R language and tested on Clostridium beijerinckii NRRL B-598. The bacterium is a typical performer in the field of biofuels production due to its ability to produce butanol. Thanks to that this bacterial organism can be of great potential from an ecological and biotechnologica

Název v anglickém jazyce

OPERON-EXPRESSER: The Innovated Gene Expression-based Algorithm for Operon Structures Inference

Popis výsledku anglicky

Current biotechnological research of bacterial genomes has huge potential due to the use of next-generation sequencing (NGS) platforms. NGS era opens paths for analysis of data for sufficient description of microorganisms with ecology and biotechnology potential in the future. Although some tools for inference of specific structures in bacterial genomes exist, their pipelines and methodologies are often based only on searching bacterial genome databases and comparison with model microorganisms. This paper deals with the design of a new algorithm for operon structures inference in bacterial genomes. The algorithm combines searching in bacterial databases and gene expression information processing. The algorithm was implemented in R language and tested on Clostridium beijerinckii NRRL B-598. The bacterium is a typical performer in the field of biofuels production due to its ability to produce butanol. Thanks to that this bacterial organism can be of great potential from an ecological and biotechnologica

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů