Evaluation of TMS Effects on the Phonation of Parkinson’s Disease Patients

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F22%3APU144914" target="_blank" >RIV/00216305:26220/22:PU144914 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1007/978-3-031-06242-1_20" target="_blank" >https://doi.org/10.1007/978-3-031-06242-1_20</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-3-031-06242-1_20" target="_blank" >10.1007/978-3-031-06242-1_20</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Evaluation of TMS Effects on the Phonation of Parkinson’s Disease Patients

Popis výsledku v původním jazyce

Repetitive Transcranial Magnetic Stimulation (rTMS) is a non-invasive technique which is known to produce modifications in cortical brain activity. This paper is devoted to describe potential beneficial effects of rTMS on the phonation stability of Parkinson’s Disease Patients (PDPs). To this end, several measurements derived from phonation have been studied. The stability of phonation is evaluated on sustained emisions of certain open vowels, as [a:]. Using vocal tract inversion, a correlate of the glottal source (pressure on the supraglottal rim of the vocal folds) is estimated from vowel emissions. The glottal source power spectral density is used to indirectly estimate the biomechanical tension of the vocal folds. The neuromotor instabilities experienced by PDPs, affecting the vocal fold tension are used as perturbation features related to tremor bands. A longitudinal analysis of the features from an active rTMS case can be compared in different time laps after rTMS, and tested against those from a similar study on a sham rTMS case. Relevant improvements on phonation stability may be appreciated on the active rTMS case compared to the sham one, which are reflected on several features as biomechanical tremor bands. These results open a new non-invasive, costless and remote methodology for PD functional neuromotor evaluation.

Název v anglickém jazyce

Evaluation of TMS Effects on the Phonation of Parkinson’s Disease Patients

Popis výsledku anglicky

Repetitive Transcranial Magnetic Stimulation (rTMS) is a non-invasive technique which is known to produce modifications in cortical brain activity. This paper is devoted to describe potential beneficial effects of rTMS on the phonation stability of Parkinson’s Disease Patients (PDPs). To this end, several measurements derived from phonation have been studied. The stability of phonation is evaluated on sustained emisions of certain open vowels, as [a:]. Using vocal tract inversion, a correlate of the glottal source (pressure on the supraglottal rim of the vocal folds) is estimated from vowel emissions. The glottal source power spectral density is used to indirectly estimate the biomechanical tension of the vocal folds. The neuromotor instabilities experienced by PDPs, affecting the vocal fold tension are used as perturbation features related to tremor bands. A longitudinal analysis of the features from an active rTMS case can be compared in different time laps after rTMS, and tested against those from a similar study on a sham rTMS case. Relevant improvements on phonation stability may be appreciated on the active rTMS case compared to the sham one, which are reflected on several features as biomechanical tremor bands. These results open a new non-invasive, costless and remote methodology for PD functional neuromotor evaluation.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

<a href="/cs/project/NV16-30805A" target="_blank" >NV16-30805A: Efekt neinvazivní stimulace mozku na hypokinetickou dysartrii, mikrografii a mozkovou plasticitu u pacientů s Parkinsonovou nemocí</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Artificial Intelligence in Neuroscience: Affective Analysis and Health Applications

ISBN

978-3-031-06242-1

ISSN

—

e-ISSN

—

Počet stran výsledku

10

Strana od-do

199-208

Název nakladatele

Springer Science and Business Media

Místo vydání

neuveden

Místo konání akce

Tenerife

Datum konání akce

3. 6. 2022

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000874361900020