Exercise-based Predictors of Late Recurrence of Atrial Fibrillation After Catheter Ablation

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Exercise-based Predictors of Late Recurrence of Atrial Fibrillation After Catheter Ablation

Popis výsledku v původním jazyce

Freedom from atrial fibrillation at 1 year is estimated to be between 55–80 % of patients undergoing catheter ablation. A significant number of them would require repeat procedures due to recurrent AF. Patients at higher risk for developing recurrent AF could benefit from different ablation strategies and post-ablation rhythm control therapy. We aim to identify the exercise-based risk factors associated with the first recurrence of AF between 3 and 36 months following the ablation. Patients (n=98, 69.4 % men) referred for catheter ablation of paroxysmal AF underwent simultaneous arm ergometry, exercise echocardiography and invasive left atrial pressure measurements. After the index ablation procedure, follow-up visits were scheduled at 1 up to 36 months. The observed freedom from AF recurrence during the follow-up was 81 %. Multivariable-adjusted Cox regression revealed the peak VO2 as the most significant predictor of late AF reccurence (hazard ratio 0.53, p<0.005). Among analyzed parameters, the lowest prediction error was achieved by including left atrial volume index, left atrial pressure and peak VO2 into age and sex adjusted Cox model (AIC=132.02, C-statistics=0.83). Presence of either decreased exercise capacity or elevated left atrial pressure is able to identify patients with potentially impaired left atrial function and different clinical outcome after conventional pulmonary vein isolation.

Název v anglickém jazyce

Exercise-based Predictors of Late Recurrence of Atrial Fibrillation After Catheter Ablation

Popis výsledku anglicky

Freedom from atrial fibrillation at 1 year is estimated to be between 55–80 % of patients undergoing catheter ablation. A significant number of them would require repeat procedures due to recurrent AF. Patients at higher risk for developing recurrent AF could benefit from different ablation strategies and post-ablation rhythm control therapy. We aim to identify the exercise-based risk factors associated with the first recurrence of AF between 3 and 36 months following the ablation. Patients (n=98, 69.4 % men) referred for catheter ablation of paroxysmal AF underwent simultaneous arm ergometry, exercise echocardiography and invasive left atrial pressure measurements. After the index ablation procedure, follow-up visits were scheduled at 1 up to 36 months. The observed freedom from AF recurrence during the follow-up was 81 %. Multivariable-adjusted Cox regression revealed the peak VO2 as the most significant predictor of late AF reccurence (hazard ratio 0.53, p<0.005). Among analyzed parameters, the lowest prediction error was achieved by including left atrial volume index, left atrial pressure and peak VO2 into age and sex adjusted Cox model (AIC=132.02, C-statistics=0.83). Presence of either decreased exercise capacity or elevated left atrial pressure is able to identify patients with potentially impaired left atrial function and different clinical outcome after conventional pulmonary vein isolation.

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Computing in Cardiology 2022

ISBN

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ISSN

2325-887X

e-ISSN

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Počet stran výsledku

4

Strana od-do

1-4

Název nakladatele

Computing in Cardiology 2022

Místo vydání

Tampere

Místo konání akce

Tampere, Finsko

Datum konání akce

3. 9. 2022

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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