T1 mapping of myocardium in rats using self-gated golden-angle acquisition

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F23%3APU149041" target="_blank" >RIV/00216305:26220/23:PU149041 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68081731:_____/24:00579323 RIV/00216224:14110/24:00135211 RIV/00159816:_____/23:00079732

Výsledek na webu

<a href="https://onlinelibrary.wiley.com/doi/10.1002/mrm.29846" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/mrm.29846</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/mrm.29846" target="_blank" >10.1002/mrm.29846</a>

Jazyk výsledku

angličtina

Název v původním jazyce

T1 mapping of myocardium in rats using self-gated golden-angle acquisition

Popis výsledku v původním jazyce

PurposeThe aim of this study is to design a method of myocardial T1 quantification in small laboratory animals and to investigate the effects of spatiotemporal regularization and the needed acquisition duration.MethodsWe propose a compressed-sensing approach to T1 quantification based on self-gated inversion-recovery radial two/three-dimensional (2D/3D) golden-angle stack-of-stars acquisition with image reconstruction performed using total-variation spatiotemporal regularization. The method was tested on a phantom and on a healthy rat, as well as on rats in a small myocardium-remodeling study.ResultsThe results showed a good match of the T1 estimates with the results obtained using the ground-truth method on a phantom and with the literature values for rats myocardium. The proposed 2D and 3D methods showed significant differences between normal and remodeling myocardium groups for acquisition lengths down to approximately 5 and 15 min, respectively.ConclusionsA new 2D and 3D method for quantification of myocardial T1 in rats was proposed. We have shown the capability of both techniques to distinguish between normal and remodeling myocardial tissue. We have shown the effects of image-reconstruction regularization weights and acquisition length on the T1 estimates.

Název v anglickém jazyce

T1 mapping of myocardium in rats using self-gated golden-angle acquisition

Popis výsledku anglicky

PurposeThe aim of this study is to design a method of myocardial T1 quantification in small laboratory animals and to investigate the effects of spatiotemporal regularization and the needed acquisition duration.MethodsWe propose a compressed-sensing approach to T1 quantification based on self-gated inversion-recovery radial two/three-dimensional (2D/3D) golden-angle stack-of-stars acquisition with image reconstruction performed using total-variation spatiotemporal regularization. The method was tested on a phantom and on a healthy rat, as well as on rats in a small myocardium-remodeling study.ResultsThe results showed a good match of the T1 estimates with the results obtained using the ground-truth method on a phantom and with the literature values for rats myocardium. The proposed 2D and 3D methods showed significant differences between normal and remodeling myocardium groups for acquisition lengths down to approximately 5 and 15 min, respectively.ConclusionsA new 2D and 3D method for quantification of myocardial T1 in rats was proposed. We have shown the capability of both techniques to distinguish between normal and remodeling myocardial tissue. We have shown the effects of image-reconstruction regularization weights and acquisition length on the T1 estimates.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20601 - Medical engineering

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

MAGNETIC RESONANCE IN MEDICINE

ISSN

0740-3194

e-ISSN

1522-2594

Svazek periodika

91

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

13

Strana od-do

368-380

Kód UT WoS článku

001077604100001

EID výsledku v databázi Scopus

2-s2.0-85173930220