Suitability of extraction methods for determination of drug residues in the river sediment

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F11%3APU93665" target="_blank" >RIV/00216305:26310/11:PU93665 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Suitability of extraction methods for determination of drug residues in the river sediment

Popis výsledku v původním jazyce

In this study, three different methods for extraction drug residues from river sediments were tested. Sulphonamide antibiotics, which belong to a group of pharmaceuticals widely used in human and veterinary medicine were selected as target compounds. They are discharged to the sewer systems together with the urine and faeces and enter to the wastewater treatment plant, where they are not completely removed. Their further negative impact on the ecosystem cannot therefore be excluded. Sulphonamide antibiotics were isolated from sample of river sediment by three different methods: ultrasonic extraction (USE), pressurized solvent extraction (PSE) and microwave-assisted extraction techniques (MAE). These three methods were compared and the most suitable method was found. Samples were concentrated and cleaned using solid phase extraction (SPE). For determination these antibiotics high performance liquid chromatography with diode array detector was used.

Název v anglickém jazyce

Suitability of extraction methods for determination of drug residues in the river sediment

Popis výsledku anglicky

In this study, three different methods for extraction drug residues from river sediments were tested. Sulphonamide antibiotics, which belong to a group of pharmaceuticals widely used in human and veterinary medicine were selected as target compounds. They are discharged to the sewer systems together with the urine and faeces and enter to the wastewater treatment plant, where they are not completely removed. Their further negative impact on the ecosystem cannot therefore be excluded. Sulphonamide antibiotics were isolated from sample of river sediment by three different methods: ultrasonic extraction (USE), pressurized solvent extraction (PSE) and microwave-assisted extraction techniques (MAE). These three methods were compared and the most suitable method was found. Samples were concentrated and cleaned using solid phase extraction (SPE). For determination these antibiotics high performance liquid chromatography with diode array detector was used.

Druh

O - Ostatní výsledky

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů