Transparent Elastomeric Polyurethanes Based on Poly(ethylene glycol) and Poly(caprolactone) for Medical Applications

Kód výsledku v IS VaVaI

RIV/00216305:26310/12:PU100764 - isvavai.cz

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Transparent Elastomeric Polyurethanes Based on Poly(ethylene glycol) and Poly(caprolactone) for Medical Applications

Popis výsledku v původním jazyce

Biodegradable polyurethane (bio-PU) elastomers with potential use as a scaffolds in regenerative medicine were synthesized by solvent free method using poly(ethylene glycol) (PEG), poly(caprolactone) (PCL) and hexamethylene diisocyanate (HMDI) catalyzedwith stannous octoate. Different diol hydrophilic (PEG) to hydrophobic (PCL) content ratios of 70:30, 50:50 and 30:70 were used. Samples made of one type of diol, either hydrophilic PEG or hydrophobic PCL, were synthesized as well. It was found that mechanical properties as well as th hydrolytic stability of resulted bio-PU elastomers might be effectively tailored by both the ratio of used diols as well as by the isocyanate ratio (ratio between OH and NCO groups).

Název v anglickém jazyce

Transparent Elastomeric Polyurethanes Based on Poly(ethylene glycol) and Poly(caprolactone) for Medical Applications

Popis výsledku anglicky

Biodegradable polyurethane (bio-PU) elastomers with potential use as a scaffolds in regenerative medicine were synthesized by solvent free method using poly(ethylene glycol) (PEG), poly(caprolactone) (PCL) and hexamethylene diisocyanate (HMDI) catalyzedwith stannous octoate. Different diol hydrophilic (PEG) to hydrophobic (PCL) content ratios of 70:30, 50:50 and 30:70 were used. Samples made of one type of diol, either hydrophilic PEG or hydrophobic PCL, were synthesized as well. It was found that mechanical properties as well as th hydrolytic stability of resulted bio-PU elastomers might be effectively tailored by both the ratio of used diols as well as by the isocyanate ratio (ratio between OH and NCO groups).

Druh

O - Ostatní výsledky

CEP obor

CD - Makromolekulární chemie

OECD FORD obor

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Projekt

ED1.1.00/02.0068: CEITEC - central european institute of technology

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů