The utilization of freeze-drying method for solubilization of hydrophobes in the hydrophilic biopolymer environment
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F15%3APU117788" target="_blank" >RIV/00216305:26310/15:PU117788 - isvavai.cz</a>
Výsledek na webu
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DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
The utilization of freeze-drying method for solubilization of hydrophobes in the hydrophilic biopolymer environment
Popis výsledku v původním jazyce
Hyaluronan is a chemical with prevalent hydrophilic character in native form. This is the main limiting factor for the formation of the interactions with hydrophobic species without additional support. The main aim of this work was to utilize freeze-drying method to support desired interactions. Hydrophobic polarity-sensitive fluorescence probes were used as hydrophobic models or indicators of interactions with hydrophobic patches. By monitoring of their specific fluorescence parameters the presence ofdesired interactions was judged. The fluorescence parameters were studied by steady state fluorescence spectrometry.
Název v anglickém jazyce
The utilization of freeze-drying method for solubilization of hydrophobes in the hydrophilic biopolymer environment
Popis výsledku anglicky
Hyaluronan is a chemical with prevalent hydrophilic character in native form. This is the main limiting factor for the formation of the interactions with hydrophobic species without additional support. The main aim of this work was to utilize freeze-drying method to support desired interactions. Hydrophobic polarity-sensitive fluorescence probes were used as hydrophobic models or indicators of interactions with hydrophobic patches. By monitoring of their specific fluorescence parameters the presence ofdesired interactions was judged. The fluorescence parameters were studied by steady state fluorescence spectrometry.
Klasifikace
Druh
O - Ostatní výsledky
CEP obor
CF - Fyzikální chemie a teoretická chemie
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2015
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů