Portable medium pressure capillary liquid chromatography based on a modular microfluidic system using off-the-shelf components

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F15%3APU118829" target="_blank" >RIV/00216305:26310/15:PU118829 - isvavai.cz</a>

Výsledek na webu

<a href="http://pittcon.org/pittcon-2015/" target="_blank" >http://pittcon.org/pittcon-2015/</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Portable medium pressure capillary liquid chromatography based on a modular microfluidic system using off-the-shelf components

Popis výsledku v původním jazyce

Here we investigated a design philosophy of a portable medium-pressure LC system based on using off-the-shelf easily accessible components. The basis of the system is a modular microfluidic platform with the components assembled in a flexible manner on abreadboard (Fig.1). The components are syringe pumps and switch valves, joined with capillaries and microfluidic fittings, complemented with other components, including an injection valve and on-capillary detectors, all controlled by a PC. The pumping system is formed by miniaturised syringe pumps (5, 20 and 100?L options). Two pairs of pumps were used for each mobile phase to enable gradient elution capability, connected with two microfluidic switching valves, and then connected together through a Y-connector, thus providing a low hold-up volume for gradient formation. A 4 or 20 nL nano-LC sampling valve was used for the injection system, connecting to a capillary LC column (100 ?m i.d., 50- 250 mm length, C18 RP monolith). Photometri

Název v anglickém jazyce

Portable medium pressure capillary liquid chromatography based on a modular microfluidic system using off-the-shelf components

Popis výsledku anglicky

Here we investigated a design philosophy of a portable medium-pressure LC system based on using off-the-shelf easily accessible components. The basis of the system is a modular microfluidic platform with the components assembled in a flexible manner on abreadboard (Fig.1). The components are syringe pumps and switch valves, joined with capillaries and microfluidic fittings, complemented with other components, including an injection valve and on-capillary detectors, all controlled by a PC. The pumping system is formed by miniaturised syringe pumps (5, 20 and 100?L options). Two pairs of pumps were used for each mobile phase to enable gradient elution capability, connected with two microfluidic switching valves, and then connected together through a Y-connector, thus providing a low hold-up volume for gradient formation. A 4 or 20 nL nano-LC sampling valve was used for the injection system, connecting to a capillary LC column (100 ?m i.d., 50- 250 mm length, C18 RP monolith). Photometri

Druh

O - Ostatní výsledky

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů