Porous HA/alumina composites intended for bone-tissue engineering

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F17%3APU124422" target="_blank" >RIV/00216305:26310/17:PU124422 - isvavai.cz</a>

Výsledek na webu

<a href="http://mit.imt.si/Revija/izvodi/mit174/bartonickova.pdf" target="_blank" >http://mit.imt.si/Revija/izvodi/mit174/bartonickova.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.17222/mit.2016.191" target="_blank" >10.17222/mit.2016.191</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Porous HA/alumina composites intended for bone-tissue engineering

Popis výsledku v původním jazyce

Ceramic biomaterials based on hydroxyapatite (HA) or alumina have been intensively studied due to their load-bearing applications in the bone-tissue replacement/reconstruction and dental applications. Here we present a study of the preparation and properties of HA/alumina (HA/Al) composites with a targeted porosity. The HA powder used for the composite's preparation was synthetized via a precipitation method under a variety of pH values. The resulting powders were verified with XRD, Raman and FTIR analyses. The particle size was assessed via SEM and laser diffraction. The as-prepared HA nanopowder and alumina powder (median 3 μm) were homogenously mixed having a composition of HA/Alumina = 90/10 (w/w). A suspension with 65 % mass fraction of the powders was properly mixed and, with the help of foaming agents, it was foamed in situ. The behavior under an increasing temperature was studied, using a heating microscope and dried foams were sintered under determined temperatures. The final sintered foams were examined in vitro in a synthetic body fluid, which predicted the behavior of bone implants in vivo. The behavior of the treated samples was studied with SEM. The newly formed HA composites were confronted with Ca2+ and PO4 3- contents in the applied body-fluid solution.

Název v anglickém jazyce

Porous HA/alumina composites intended for bone-tissue engineering

Popis výsledku anglicky

Ceramic biomaterials based on hydroxyapatite (HA) or alumina have been intensively studied due to their load-bearing applications in the bone-tissue replacement/reconstruction and dental applications. Here we present a study of the preparation and properties of HA/alumina (HA/Al) composites with a targeted porosity. The HA powder used for the composite's preparation was synthetized via a precipitation method under a variety of pH values. The resulting powders were verified with XRD, Raman and FTIR analyses. The particle size was assessed via SEM and laser diffraction. The as-prepared HA nanopowder and alumina powder (median 3 μm) were homogenously mixed having a composition of HA/Alumina = 90/10 (w/w). A suspension with 65 % mass fraction of the powders was properly mixed and, with the help of foaming agents, it was foamed in situ. The behavior under an increasing temperature was studied, using a heating microscope and dried foams were sintered under determined temperatures. The final sintered foams were examined in vitro in a synthetic body fluid, which predicted the behavior of bone implants in vivo. The behavior of the treated samples was studied with SEM. The newly formed HA composites were confronted with Ca2+ and PO4 3- contents in the applied body-fluid solution.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20504 - Ceramics

Projekt

<a href="/cs/project/LO1211" target="_blank" >LO1211: Centrum materiálového výzkumu na FCH VUT v Brně - udržitelnost a rozvoj</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Materiali in tehnologije

ISSN

1580-2949

e-ISSN

1580-3414

Svazek periodika

51

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

SI - Slovinská republika

Počet stran výsledku

6

Strana od-do

631-636

Kód UT WoS článku

000408399700013

EID výsledku v databázi Scopus

2-s2.0-85026314532