Transport of organic dyes in bioplymeric hydrogels

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Transport of organic dyes in bioplymeric hydrogels

Popis výsledku v původním jazyce

Biopolymeric hydrogels based on oppositely charged polyelectrolytes and surfactants can contain micelle-like nanostructures potentially usable for medical applications. Integration of the nanocontainers for pharmaceutically active substances into hydrogel matrix can solve problems with their hydrophobic nature. Interactions of biopolymeric electrolytes with oppositely charged surfactants which can result in dissolving hydrophobes in micelle-like nanocontainers formed by surfactants. In this study, hydrogels were prepared either from hyaluronan and cationic surfactant septonex (carbethoxypendecinium bromide) or from diethylaminoethyl dextrane and sodium dodecylsulphate as described previously. Nile red was used as a model diffusion probe in order to investigate the release of active substances from hydrogel. The probe was incorporated into hydrogel structures in their preparations and its release was monitored in time by UV/VIS spectrometry. It was found that the equilibrium between the formed hydroge

Název v anglickém jazyce

Transport of organic dyes in bioplymeric hydrogels

Popis výsledku anglicky

Biopolymeric hydrogels based on oppositely charged polyelectrolytes and surfactants can contain micelle-like nanostructures potentially usable for medical applications. Integration of the nanocontainers for pharmaceutically active substances into hydrogel matrix can solve problems with their hydrophobic nature. Interactions of biopolymeric electrolytes with oppositely charged surfactants which can result in dissolving hydrophobes in micelle-like nanocontainers formed by surfactants. In this study, hydrogels were prepared either from hyaluronan and cationic surfactant septonex (carbethoxypendecinium bromide) or from diethylaminoethyl dextrane and sodium dodecylsulphate as described previously. Nile red was used as a model diffusion probe in order to investigate the release of active substances from hydrogel. The probe was incorporated into hydrogel structures in their preparations and its release was monitored in time by UV/VIS spectrometry. It was found that the equilibrium between the formed hydroge

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10403 - Physical chemistry

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů