Novel unexpected functions of PHA granules

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F20%3APU136594" target="_blank" >RIV/00216305:26310/20:PU136594 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/article/10.1007/s00253-020-10568-1" target="_blank" >https://link.springer.com/article/10.1007/s00253-020-10568-1</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00253-020-10568-1" target="_blank" >10.1007/s00253-020-10568-1</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Novel unexpected functions of PHA granules

Popis výsledku v původním jazyce

Polyhydroxyalkanoates (PHA), polyesters accumulated by numerous prokaryotes in the form of intracellular granules, have been for decades considered being predominantly storage molecules. However, numerous recent discoveries revealed and emphasized their complex biological role for microbial cells. Most of all, it was repeatedly reported and confirmed that the presence of PHA granules in prokaryotic cells enhances stress resistance and robustness of microbes against various environmental stress factors such as high or low temperature, freezing, oxidative, and osmotic pressure. It seems that protective mechanisms of PHA granules are associated with their extraordinary architecture and biophysical properties as well as with the complex and deeply interconnected nature of PHA metabolism. Therefore, this review aims at describing novel and unexpected properties of PHA granules with respect to their contribution to stress tolerance of various prokaryotes including common mesophilic heterotrophic bacteria, but also extremophiles or photo-autotrophic cyanobacteria.

Název v anglickém jazyce

Novel unexpected functions of PHA granules

Popis výsledku anglicky

Polyhydroxyalkanoates (PHA), polyesters accumulated by numerous prokaryotes in the form of intracellular granules, have been for decades considered being predominantly storage molecules. However, numerous recent discoveries revealed and emphasized their complex biological role for microbial cells. Most of all, it was repeatedly reported and confirmed that the presence of PHA granules in prokaryotic cells enhances stress resistance and robustness of microbes against various environmental stress factors such as high or low temperature, freezing, oxidative, and osmotic pressure. It seems that protective mechanisms of PHA granules are associated with their extraordinary architecture and biophysical properties as well as with the complex and deeply interconnected nature of PHA metabolism. Therefore, this review aims at describing novel and unexpected properties of PHA granules with respect to their contribution to stress tolerance of various prokaryotes including common mesophilic heterotrophic bacteria, but also extremophiles or photo-autotrophic cyanobacteria.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20801 - Environmental biotechnology

Projekt

<a href="/cs/project/GA19-20697S" target="_blank" >GA19-20697S: Řízená evoluce bakterií produkujících polyhydroxyalkanoáty</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

ISSN

0175-7598

e-ISSN

1432-0614

Svazek periodika

104

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

16

Strana od-do

4795-4810

Kód UT WoS článku

000533083000009

EID výsledku v databázi Scopus

2-s2.0-85083833819