Peptide nucleic acid stabilized perovskite nanoparticles for nucleic acid sensing
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F20%3APU137541" target="_blank" >RIV/00216305:26310/20:PU137541 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/61989592:15310/20:73604403
Výsledek na webu
<a href="https://pdf.sciencedirectassets.com/315457/1-s2.0-S2468519420X00036/1-s2.0-S246851942030032X/main.pdf?X-Amz-Date=20201023T102706Z&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Signature=13bfecd58d5c59d292a8c1c5c2bd750ddcac7d1555150e30e39054b483197a3a&X-Amz-Cred" target="_blank" >https://pdf.sciencedirectassets.com/315457/1-s2.0-S2468519420X00036/1-s2.0-S246851942030032X/main.pdf?X-Amz-Date=20201023T102706Z&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Signature=13bfecd58d5c59d292a8c1c5c2bd750ddcac7d1555150e30e39054b483197a3a&X-Amz-Cred</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.mtchem.2020.100272" target="_blank" >10.1016/j.mtchem.2020.100272</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Peptide nucleic acid stabilized perovskite nanoparticles for nucleic acid sensing
Popis výsledku v původním jazyce
Nanostructural hybrid organic-inorganic metal halide perovskites offer a wide range of potential applications including photovoltaics, solar cells, and light emitting diodes. Up to now the surface stabilizing ligands were used solely to obtain the optimal properties of nanoparticles in terms of dimensionality and stability, however their possible additional functionality was rarely considered. In the present work, hybrid lead bromide perovskite nanoparticles (PNP) were prepared using a unique approach where a peptide nucleic acid is used as a surface ligand. Methylammonium lead bromide perovskite colloidal nanoparticles stabilized by thymine-based peptide nucleic acid monomer (PNA-M) and relevant trimer (PNA-T) were prepared exhibiting the size below 10 nm. Perovskite structure and crystallinity were verified by X-ray powder diffraction spectroscopy and high resolution transmission electron microscopy. PNP-PNA-M and PNP-PNA-T colloidal dispersions in chloroform and toluene possessed green-blue fluorescence, while Fourier-transform infrared spectroscopy (FT-IR) and quantum chemical calculations showed that the PNA coordinates to the PNP surface through the primary amine group. Additionally, the sensing ability of the PNA ligand for adenine nucleic acid was demonstrated by photoluminescence quenching via charge transfer. Furthermore, PNP thin films were effectively produced by the centrifugal casting. We envision that combining the unique, tailored structure of peptide nucleic acids and the prospective optical features of lead halide perovskite nanoparticles could expand the field of applications of such hybrids exploiting analogous ligand chemistry. (C) 2020 The Author(s). Published by Elsevier Ltd.
Název v anglickém jazyce
Peptide nucleic acid stabilized perovskite nanoparticles for nucleic acid sensing
Popis výsledku anglicky
Nanostructural hybrid organic-inorganic metal halide perovskites offer a wide range of potential applications including photovoltaics, solar cells, and light emitting diodes. Up to now the surface stabilizing ligands were used solely to obtain the optimal properties of nanoparticles in terms of dimensionality and stability, however their possible additional functionality was rarely considered. In the present work, hybrid lead bromide perovskite nanoparticles (PNP) were prepared using a unique approach where a peptide nucleic acid is used as a surface ligand. Methylammonium lead bromide perovskite colloidal nanoparticles stabilized by thymine-based peptide nucleic acid monomer (PNA-M) and relevant trimer (PNA-T) were prepared exhibiting the size below 10 nm. Perovskite structure and crystallinity were verified by X-ray powder diffraction spectroscopy and high resolution transmission electron microscopy. PNP-PNA-M and PNP-PNA-T colloidal dispersions in chloroform and toluene possessed green-blue fluorescence, while Fourier-transform infrared spectroscopy (FT-IR) and quantum chemical calculations showed that the PNA coordinates to the PNP surface through the primary amine group. Additionally, the sensing ability of the PNA ligand for adenine nucleic acid was demonstrated by photoluminescence quenching via charge transfer. Furthermore, PNP thin films were effectively produced by the centrifugal casting. We envision that combining the unique, tailored structure of peptide nucleic acids and the prospective optical features of lead halide perovskite nanoparticles could expand the field of applications of such hybrids exploiting analogous ligand chemistry. (C) 2020 The Author(s). Published by Elsevier Ltd.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10403 - Physical chemistry
Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2020
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Materials Today Chemistry
ISSN
2468-5194
e-ISSN
—
Svazek periodika
17
Číslo periodika v rámci svazku
1
Stát vydavatele periodika
NL - Nizozemsko
Počet stran výsledku
8
Strana od-do
1-8
Kód UT WoS článku
000572168300002
EID výsledku v databázi Scopus
2-s2.0-85084474235