Production of P(3HB-co-4HB) copolymer by new thermophilic isolate Aneurinibacillus sp. H1 in batch, repated-batch and fed-batch cultivation modes of cultivation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F21%3APU139729" target="_blank" >RIV/00216305:26310/21:PU139729 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Production of P(3HB-co-4HB) copolymer by new thermophilic isolate Aneurinibacillus sp. H1 in batch, repated-batch and fed-batch cultivation modes of cultivation

Popis výsledku v původním jazyce

Extremophilic organisms are promising producers of biotechnological productions, because thanks to living in extreme conditions the biotechnological process is not so demanding on sterility and the biotechnological price of production is cheaper. Polyhydroxyalkanoates are microbial polyesters that are fully degradable and biocompatible. They are also a good alternative to petroleum polymers. Using our original protocol to isolate thermophilic PHA producers from natural source, we isolated the bacteria, which, was designated as Aneurinibacillus sp. H1. This bacterium is capable of producing poly(3-hydroxybutyrate) (P3HB) on glycerol (even on waste glycerol) , and, furthermore, when supplemented with proper precursors, it is able to produce copolymer poly(3-hydroxybutyrate-co-3-hydroxyvalerate) or poly(3-hydroxybutyrate-co-4-hydroxybutyrate) or even terpolymer poly(3-hydroxybutyrate-co-4-hydroxybutyrate-co-3-hydroxyvalerate) with very high 4-hydroxybutyrate and 3-hydroxyvalerate fractions.

Název v anglickém jazyce

Production of P(3HB-co-4HB) copolymer by new thermophilic isolate Aneurinibacillus sp. H1 in batch, repated-batch and fed-batch cultivation modes of cultivation

Popis výsledku anglicky

Extremophilic organisms are promising producers of biotechnological productions, because thanks to living in extreme conditions the biotechnological process is not so demanding on sterility and the biotechnological price of production is cheaper. Polyhydroxyalkanoates are microbial polyesters that are fully degradable and biocompatible. They are also a good alternative to petroleum polymers. Using our original protocol to isolate thermophilic PHA producers from natural source, we isolated the bacteria, which, was designated as Aneurinibacillus sp. H1. This bacterium is capable of producing poly(3-hydroxybutyrate) (P3HB) on glycerol (even on waste glycerol) , and, furthermore, when supplemented with proper precursors, it is able to produce copolymer poly(3-hydroxybutyrate-co-3-hydroxyvalerate) or poly(3-hydroxybutyrate-co-4-hydroxybutyrate) or even terpolymer poly(3-hydroxybutyrate-co-4-hydroxybutyrate-co-3-hydroxyvalerate) with very high 4-hydroxybutyrate and 3-hydroxyvalerate fractions.

Druh

O - Ostatní výsledky

CEP obor

—

OECD FORD obor

10606 - Microbiology

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů