Digging deeper into the mother-offspring transfer of selenium through human breast milk

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F21%3APU141242" target="_blank" >RIV/00216305:26310/21:PU141242 - isvavai.cz</a>

Výsledek na webu

<a href="https://www-sciencedirect-com.ezproxy.lib.vutbr.cz/science/article/pii/S0889157521000703" target="_blank" >https://www-sciencedirect-com.ezproxy.lib.vutbr.cz/science/article/pii/S0889157521000703</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jfca.2021.103870" target="_blank" >10.1016/j.jfca.2021.103870</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Digging deeper into the mother-offspring transfer of selenium through human breast milk

Popis výsledku v původním jazyce

Selenoprotein P contains most of the selenium in plasma and favours selenium retention in the brain over other organs. Recently, the presence of selenoprotein P in human breast milk has been demonstrated, filling the gap around the mother-offspring transfer of selenium during lactation and through cord serum. In this work, selenometabolites and selenoproteins have been accurately determined in human breast milk and cord and maternal sera. Using a heteroatom tagged proteomic method, twenty mother-child couples were analysed. The mean total concentration in maternal serum was 90 ± 10 ng Se g−1 (1.33 and 1.52-fold higher than that in cord serum and human breast milk, respectively). The concentration of selenoprotein P (ng Se g−1) follows the order: maternal serum (57.1 ± 8.8) > cord serum (33.6 ± 4.2) > breast milk (18.8 ± 5.1). Glutathione peroxidase was mainly transferred by breast milk, selenometabolites were transferred by breast milk and cord serum and selenocystamine was only present in breast milk.

Název v anglickém jazyce

Digging deeper into the mother-offspring transfer of selenium through human breast milk

Popis výsledku anglicky

Selenoprotein P contains most of the selenium in plasma and favours selenium retention in the brain over other organs. Recently, the presence of selenoprotein P in human breast milk has been demonstrated, filling the gap around the mother-offspring transfer of selenium during lactation and through cord serum. In this work, selenometabolites and selenoproteins have been accurately determined in human breast milk and cord and maternal sera. Using a heteroatom tagged proteomic method, twenty mother-child couples were analysed. The mean total concentration in maternal serum was 90 ± 10 ng Se g−1 (1.33 and 1.52-fold higher than that in cord serum and human breast milk, respectively). The concentration of selenoprotein P (ng Se g−1) follows the order: maternal serum (57.1 ± 8.8) > cord serum (33.6 ± 4.2) > breast milk (18.8 ± 5.1). Glutathione peroxidase was mainly transferred by breast milk, selenometabolites were transferred by breast milk and cord serum and selenocystamine was only present in breast milk.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20602 - Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

JOURNAL OF FOOD COMPOSITION AND ANALYSIS

ISSN

0889-1575

e-ISSN

1096-0481

Svazek periodika

99

Číslo periodika v rámci svazku

103870

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

1-8

Kód UT WoS článku

000701770600004

EID výsledku v databázi Scopus

2-s2.0-85102473919