Lecithin as internal architecture modifier of hydrogels for model drug delivery systems with tunable properties

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F21%3APU141798" target="_blank" >RIV/00216305:26310/21:PU141798 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Lecithin as internal architecture modifier of hydrogels for model drug delivery systems with tunable properties

Popis výsledku v původním jazyce

The purpose of this study focuses on the current and still developing topic of micro- and nanosized drug delivery systems, since their usage in treatment procedure offers a variety of benefits compared to conventional drug dosing. In recent years, specific extracellular matrix (ECM) imitating biopolymers carry exceptional properties of biocompatible and biodegradable materials, which are able to form soft or semi-solid networks beneficial for drug incorporation. Recent studies of innovative complex biomaterials have proved the potential of hydrogels usage for fabrication of novel materials, providing appropriate mechanical, chemical and biological characteristic for mimicking ECM for regenerative medicine, fabrication and in situ analyses of drug delivery systems [1-3]. Final properties related to specific application of these materials can be modified not only by polymer and/or crosslinking agent type and concentration, but actively also with other additives influencing inner architecture like pho

Název v anglickém jazyce

Lecithin as internal architecture modifier of hydrogels for model drug delivery systems with tunable properties

Popis výsledku anglicky

The purpose of this study focuses on the current and still developing topic of micro- and nanosized drug delivery systems, since their usage in treatment procedure offers a variety of benefits compared to conventional drug dosing. In recent years, specific extracellular matrix (ECM) imitating biopolymers carry exceptional properties of biocompatible and biodegradable materials, which are able to form soft or semi-solid networks beneficial for drug incorporation. Recent studies of innovative complex biomaterials have proved the potential of hydrogels usage for fabrication of novel materials, providing appropriate mechanical, chemical and biological characteristic for mimicking ECM for regenerative medicine, fabrication and in situ analyses of drug delivery systems [1-3]. Final properties related to specific application of these materials can be modified not only by polymer and/or crosslinking agent type and concentration, but actively also with other additives influencing inner architecture like pho

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10403 - Physical chemistry

Projekt

<a href="/cs/project/EF19_073%2F0016948" target="_blank" >EF19_073/0016948: Kvalitní interní granty VUT</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů