Experimental evaluation of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) applicability in biomedicine

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F21%3APU142566" target="_blank" >RIV/00216305:26310/21:PU142566 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Experimental evaluation of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) applicability in biomedicine

Popis výsledku v původním jazyce

Bioplastics are recently presumed as a convenient solution of the world pollution. In the foreground, group of bacterial biopolymers – polyhyd-roxyalkanoates, tends to satisfy several demands placed on these materials. Amongst PHAs, copolymer of 3-hydroxybutyrate and 4-hydroxy-butyrate – P(3HB-co-4HB) presents promising properties for wide range of applications. This potential bioplastic is naturally accumulated by a thermophilic strain Aneurinibacillus sp. H1. Since this producent is a Gram-positive bacterium, it does not produce endotoxins and is willing to generate adjustable monomer-ratio polymer according to cultivation conditions.In this study, we present crucial biophysical properties of copolymer P(3HB-co-4HB) manufactured by employing Aneurinibacillus sp. H1, in order to evaluate its applicability in biomedicine. Two different-ratio copolymers were produced, as a referential material, homopolymer pol-y-3-hydroxybutyrate was manufactured by cultivating mesophilic bacterium Cupriavidius necator

Název v anglickém jazyce

Experimental evaluation of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) applicability in biomedicine

Popis výsledku anglicky

Bioplastics are recently presumed as a convenient solution of the world pollution. In the foreground, group of bacterial biopolymers – polyhyd-roxyalkanoates, tends to satisfy several demands placed on these materials. Amongst PHAs, copolymer of 3-hydroxybutyrate and 4-hydroxy-butyrate – P(3HB-co-4HB) presents promising properties for wide range of applications. This potential bioplastic is naturally accumulated by a thermophilic strain Aneurinibacillus sp. H1. Since this producent is a Gram-positive bacterium, it does not produce endotoxins and is willing to generate adjustable monomer-ratio polymer according to cultivation conditions.In this study, we present crucial biophysical properties of copolymer P(3HB-co-4HB) manufactured by employing Aneurinibacillus sp. H1, in order to evaluate its applicability in biomedicine. Two different-ratio copolymers were produced, as a referential material, homopolymer pol-y-3-hydroxybutyrate was manufactured by cultivating mesophilic bacterium Cupriavidius necator

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

Projekt

<a href="/cs/project/EF19_073%2F0016948" target="_blank" >EF19_073/0016948: Kvalitní interní granty VUT</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů